印度妊娠高血压疾病的流行病学

Praveen Singh, Pooja Arnote, Kajal Thakur
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摘要

目的通过比较定点尿蛋白/肌酐比值与传统的 24 小时尿蛋白收集法,评估先兆子痫孕妇的蛋白尿量。研究目的:评估定点尿蛋白/肌酐比值对这一特殊患者群体蛋白尿的诊断准确性和实用性。方法:横向研究。年龄在 18 至 40 岁之间,胎龄大于 20 w,诊断为高血压(血压≥140/90 mmHg)并伴有蛋白尿是选择标准。慢性肾脏疾病、复发性尿路感染、在 24 小时尿液收集期之前出生均被视为排除因素。结果:平均年龄为 28.9 岁,初产妇占 45.55%,多产妇占 65.55%。收缩压:94.98 mmHg±8.54。肝功能异常包括总胆红素(90%)、谷丙转氨酶(60%)和谷草转氨酶(60%)。24 小时尿蛋白平均值:1884 mg/d±2562。结论:印度的 HDP 流行病学十分复杂,受到多种变量的影响。研究和医疗干预措施必须因地制宜。在这个多元文化的国家,更多的研究对于管理和预防问题至关重要。
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EPIDEMIOLOGY OF HYPERTENSIVE DISORDERS OF PREGNANCY IN INDIA
Objective: To assess the amount of proteinuria in preeclamptic pregnant women by comparing the spot urine protein/creatinine ratio with the traditional 24 h urine protein collection method. The purpose of the study was to evaluate the spot urine protein/creatinine ratio's diagnostic accuracy and usefulness for proteinuria in this particular patient group. Methods: transversal research. Ages 18 to 40, gestational age greater than 20 w, and a diagnosis of hypertension (BP ≥140/90 mmHg) with proteinuria are the selection criteria. Chronic renal illness, recurrent urinary tract infections, birth prior to a 24 h urine collection period are all considered exclusion factors. Results: 28.9 y is the mean age, with 45.55% primigravida and 65.55% multigravida. Systolic blood pressure: 94.98 mmHg±8.54. Abnormalities in liver function include total bilirubin (90%), ALT (60%), and AST (60%). Urine protein average over 24 h: 1884 mg/d±2562. Conclusion: India's HDP epidemiology is complicated and impacted by a wide range of variables. Research and medical interventions must be customized. Additional research is essential for managing and preventing problems in this multicultural country.
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