Jeong So, Hak-Dong Lee, Ji Hyun Kim, Sanghyun Lee, Jin Hee Lim
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Notably, <i>C. zawadskii</i> var. <i>lucidum</i> displayed higher antioxidant activity due to its elevated flavonoid content and potent radical scavenging activity compared to other wild <i>Chrysanthemum</i> flowers. Furthermore, <i>C. makinoi</i> exhibited strong in vitro tyrosinase inhibitory activity and reduced melanin contents in comparison to the other wild <i>Chrysanthemum</i> flowers. Our findings also confirmed the antimicrobial activity of the wild <i>Chrysanthemum</i> flower extracts against <i>Staphylococcus aureus, Pseudomonas aeruginosa,</i> and <i>Candida albicans</i>. Additionally, our HPLC analyses revealed that C. <i>zawadskii</i> var. <i>lucidum</i> had significantly higher contents of chlorogenic acid, linarin, 3,5-di-<i>O</i>-caffeoylquinic acid, and 4,5-di-<i>O</i>-caffeoylquinic acid. 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引用次数: 0
摘要
为了评估韩国野菊花作为化妆品成分的潜力,本研究评估了 Chrysanthemum zawadskii var. latilobum、C. zawadskii var.随后,对这些提取物中的酚类化合物含量进行了高效液相色谱分析。体外自由基清除活性实验证明,韩国野菊花具有很强的抗氧化性。它们还通过抑制α-黑色素细胞刺激素诱导的 B16F10 细胞中的黑色素含量,表现出美白皮肤的活性。值得注意的是,与其他野生菊花相比,C. zawadskii var.此外,与其他野菊花相比,C. makinoi 表现出较强的体外酪氨酸酶抑制活性,并降低了黑色素含量。我们的研究结果还证实了野菊花萃取物对金黄色葡萄球菌、绿脓杆菌和白色念珠菌的抗菌活性。此外,我们的高效液相色谱分析显示,C. zawadskii var. lucidum 的绿原酸、亚麻仁素、3,5-二-O-咖啡酰奎宁酸和 4,5- 二-O-咖啡酰奎宁酸含量明显更高。因此,韩国野菊花具有抗氧化、抗菌、美白肌肤的功效,而且酚类化合物含量较高,有望成为功能性化妆品成分。
Antioxidant, antimicrobial, and skin-whitening effects and quantitative analysis of phenolic compounds in Korean wild Chrysanthemum flowers via HPLC/UV
To assess the potential of Korean wild Chrysanthemum flowers as cosmetic ingredients, this study evaluated the antioxidant, antimicrobial, and skin-whitening activities of extracts from Chrysanthemum zawadskii var. latilobum, C. zawadskii var. lucidum, C. zawadskii var. yezoense, and C. makinoi. Subsequently, HPLC analyses were conducted to characterize the phenolic compound contents of these extracts. The Korean wild Chrysanthemum flowers exhibited strong antioxidant properties, as evidenced by in vitro radical scavenging activity assays. They also exhibited skin-whitening activity by inhibiting melanin contents in α-melanocyte-stimulating hormone-induced B16F10 cells. Notably, C. zawadskii var. lucidum displayed higher antioxidant activity due to its elevated flavonoid content and potent radical scavenging activity compared to other wild Chrysanthemum flowers. Furthermore, C. makinoi exhibited strong in vitro tyrosinase inhibitory activity and reduced melanin contents in comparison to the other wild Chrysanthemum flowers. Our findings also confirmed the antimicrobial activity of the wild Chrysanthemum flower extracts against Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans. Additionally, our HPLC analyses revealed that C. zawadskii var. lucidum had significantly higher contents of chlorogenic acid, linarin, 3,5-di-O-caffeoylquinic acid, and 4,5-di-O-caffeoylquinic acid. Therefore, Korean wild Chrysanthemum flowers hold promise as functional cosmetic ingredients due to their antioxidant, antimicrobial, and skin-whitening effects, as well as their elevated levels of phenolic compounds.
期刊介绍:
Horticulture, Environment, and Biotechnology (HEB) is the official journal of the Korean Society for Horticultural Science, was launched in 1965 as the "Journal of Korean Society for Horticultural Science".
HEB is an international journal, published in English, bimonthly on the last day of even number months, and indexed in Biosys Preview, SCIE, and CABI.
The journal is devoted for the publication of original research papers and review articles related to vegetables, fruits, ornamental and herbal plants, and covers all aspects of physiology, molecular biology, biotechnology, protected cultivation, postharvest technology, and research in plants related to environment.