预测创伤后应激障碍的风险和保护因素:系统综述

Kristen Jones , Mark Boschen , Grant Devilly , Jessica Vogler , Harley Flowers , Charlotte Winkleman , Martin Wullschleger
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摘要

创伤后应激障碍(PTSD)是创伤后最常见的精神疾病之一,在创伤中心收治的成年人中,PTSD 患者高达 51%。识别创伤后应激障碍的高危人群是创伤中心循证整体护理的重要组成部分。这也逐渐成为全球一级创伤中心的一项建议。本文旨在系统回顾已发表的文献,这些文献涉及在创伤医院住院一年内增加或减少创伤后应激障碍风险的因素。本文采用了系统性综述方法,并使用了广泛的检索标准。这种扩大搜索范围的策略可解决相关论文标题和摘要中的一些局限性问题。对纳入的论文进行正向和反向引用,以确定二手资料来源。标题、摘要和全文由两位作者独立审阅。有 61 篇论文符合纳入标准,对 58 项预测因素进行了至少一项分析。有强有力的科学证据表明,袭击、急性应激障碍和基线疼痛是创伤后应激障碍的预测因素。有强有力的科学证据表明,年龄、教育程度、种族、病前健康状况、婚姻状况、受伤严重程度、受伤机制和住院时间不是预测因素。在所收录的论文中发现了一些方法学方面的问题,如预测因子的操作定义存在差异,以及缺乏对创伤后应激障碍理论框架的应用。关于创伤后应激障碍认知模型等著名框架中包含的风险因素的影响,文献中仍存在空白,需要未来的研究为这一高危人群提供适当的早期干预信息。
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Risk and protective factors that predict posttraumatic stress disorder after traumatic injury: A systematic review

Posttraumatic stress disorder (PTSD) is one of the most common psychiatric disorders following traumatic injury, affecting up to 51 % of adults admitted to trauma centres. Identification of people at risk of PTSD is an important component of holistic, evidence-based care in trauma centres. This is also increasingly becoming a recommendation across Level 1 Trauma Centres worldwide. The purpose of this paper was to systematically review published literature regarding factors that increase or decrease one's risk of PTSD within a year of admission to a trauma hospital. Systematic review methodology was implemented with utilisation of extensive search criteria. This broadened search strategy was used to address some identified limitations in titles and abstracts of relevant papers. Forward and backward citation of included papers was implemented to ascertain secondary sources. Titles, abstracts, and full texts were independently reviewed by two authors. Sixty-one papers met inclusion criteria and 58 predictors were analysed with at least one analysis. There was strong scientific evidence for assault, acute stress disorder, and baseline pain as predictors of PTSD. There was strong scientific evidence that age, education, ethnicity, premorbid health concerns, marital status, injury severity, mechanism of injury, and length of stay were not predictors. Several methodological concerns were identified across the included papers, such as heterogeneity in operational definitions of predictors and lack of application to theoretical frameworks of PTSD. Gaps remain in the literature regarding the impact of risk factors included in well-known frameworks such as the cognitive model of PTSD, requiring future research to inform appropriate early intervention in this at-risk population.

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Health sciences review (Oxford, England)
Health sciences review (Oxford, England) Medicine and Dentistry (General)
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