通过机械三叶主动脉瓣和双叶主动脉瓣的血流比较分析。

IF 0.8 4区 医学 Q4 BIOPHYSICS Acta of bioengineering and biomechanics Pub Date : 2022-01-01
Marek Pawlikowski, Anna Nieroda
{"title":"通过机械三叶主动脉瓣和双叶主动脉瓣的血流比较分析。","authors":"Marek Pawlikowski, Anna Nieroda","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>The primary aim of the present study was to compare the bileaflet and trileaflet aortic valves' performance during uniform blood flow model and boundary conditions. The secondary aim of the study was to determine the effect of Newtonian/non-Newtonian fluid flow assumption on blood flow directly behind the trileaflet valve.</p><p><strong>Methods: </strong>The geometrical model of the whole system consist of the left ventricle, fragment of the aorta and mechanical valves. A representation of pulsatile flow was obtained by measuring blood flow velocity (Doppler ultrasound examination). We have assumed turbulent blood flow. We considered two blood models, Newtonian and non-Newtonian (Carreau model). The valves' performance was assessed using the reduced stress in the valves, the shear stress in the aortic wall, flow velocity field and the effective orifice area.</p><p><strong>Results: </strong>The maximum von Mises stress for the bileaflet valve leaflets was 0.3 MPa and for the trileaflet valve - 0.06 MPa. The maximum flow velocity for the bileaflet valve was 4.52 m/s for 40° and for the trileaflet valve - 5.74 m/s. Higher shear stress was present in the bileaflet (151.5 Pa) than for the trileaflet valve (49.64 Pa).</p><p><strong>Conclusions: </strong>The results indicate that central blood jet for the trileaflet valve contributes to more physiological blood flow and decreases the risk of haemolysis. The central flow minimises the risk of leaflet dislocation. In addition, lower stresses extend the durability of the valve. However, the trileaflet valve geometry has also disadvantages, for instance, small peripheral streams or relatively low effective orifice area.</p>","PeriodicalId":6897,"journal":{"name":"Acta of bioengineering and biomechanics","volume":null,"pages":null},"PeriodicalIF":0.8000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparative analyses of blood flow through mechanical trileaflet and bileaflet aortic valves.\",\"authors\":\"Marek Pawlikowski, Anna Nieroda\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>The primary aim of the present study was to compare the bileaflet and trileaflet aortic valves' performance during uniform blood flow model and boundary conditions. The secondary aim of the study was to determine the effect of Newtonian/non-Newtonian fluid flow assumption on blood flow directly behind the trileaflet valve.</p><p><strong>Methods: </strong>The geometrical model of the whole system consist of the left ventricle, fragment of the aorta and mechanical valves. A representation of pulsatile flow was obtained by measuring blood flow velocity (Doppler ultrasound examination). We have assumed turbulent blood flow. We considered two blood models, Newtonian and non-Newtonian (Carreau model). The valves' performance was assessed using the reduced stress in the valves, the shear stress in the aortic wall, flow velocity field and the effective orifice area.</p><p><strong>Results: </strong>The maximum von Mises stress for the bileaflet valve leaflets was 0.3 MPa and for the trileaflet valve - 0.06 MPa. The maximum flow velocity for the bileaflet valve was 4.52 m/s for 40° and for the trileaflet valve - 5.74 m/s. Higher shear stress was present in the bileaflet (151.5 Pa) than for the trileaflet valve (49.64 Pa).</p><p><strong>Conclusions: </strong>The results indicate that central blood jet for the trileaflet valve contributes to more physiological blood flow and decreases the risk of haemolysis. The central flow minimises the risk of leaflet dislocation. In addition, lower stresses extend the durability of the valve. However, the trileaflet valve geometry has also disadvantages, for instance, small peripheral streams or relatively low effective orifice area.</p>\",\"PeriodicalId\":6897,\"journal\":{\"name\":\"Acta of bioengineering and biomechanics\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2022-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta of bioengineering and biomechanics\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"BIOPHYSICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta of bioengineering and biomechanics","FirstCategoryId":"5","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOPHYSICS","Score":null,"Total":0}
引用次数: 0

摘要

目的:本研究的主要目的是比较双叶主动脉瓣和三叶主动脉瓣在均匀血流模型和边界条件下的性能。研究的次要目的是确定牛顿/非牛顿流体流动假设对三叶瓣正后方血流的影响:整个系统的几何模型由左心室、主动脉片段和机械瓣膜组成。通过测量血流速度(多普勒超声检查)获得搏动血流的表现。我们假设血流为湍流。我们考虑了牛顿和非牛顿(Carreau 模型)两种血液模型。瓣膜的性能是通过瓣膜的减应力、主动脉壁的剪应力、流速场和有效孔面积来评估的:结果:双叶瓣的最大 von Mises 应力为 0.3 兆帕,三叶瓣为 0.06 兆帕。双叶瓣在 40° 时的最大流速为 4.52 米/秒,三叶瓣为 5.74 米/秒。双叶瓣的剪应力(151.5 帕)高于三叶瓣(49.64 帕):结果表明,三叶瓣的中心血流喷射有助于增加生理血流量,降低溶血风险。中心血流可将瓣叶脱位的风险降至最低。此外,较低的应力也延长了瓣膜的耐用性。不过,三叶瓣的几何形状也有缺点,例如外周血流较小或有效孔面积相对较小。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Comparative analyses of blood flow through mechanical trileaflet and bileaflet aortic valves.

Purpose: The primary aim of the present study was to compare the bileaflet and trileaflet aortic valves' performance during uniform blood flow model and boundary conditions. The secondary aim of the study was to determine the effect of Newtonian/non-Newtonian fluid flow assumption on blood flow directly behind the trileaflet valve.

Methods: The geometrical model of the whole system consist of the left ventricle, fragment of the aorta and mechanical valves. A representation of pulsatile flow was obtained by measuring blood flow velocity (Doppler ultrasound examination). We have assumed turbulent blood flow. We considered two blood models, Newtonian and non-Newtonian (Carreau model). The valves' performance was assessed using the reduced stress in the valves, the shear stress in the aortic wall, flow velocity field and the effective orifice area.

Results: The maximum von Mises stress for the bileaflet valve leaflets was 0.3 MPa and for the trileaflet valve - 0.06 MPa. The maximum flow velocity for the bileaflet valve was 4.52 m/s for 40° and for the trileaflet valve - 5.74 m/s. Higher shear stress was present in the bileaflet (151.5 Pa) than for the trileaflet valve (49.64 Pa).

Conclusions: The results indicate that central blood jet for the trileaflet valve contributes to more physiological blood flow and decreases the risk of haemolysis. The central flow minimises the risk of leaflet dislocation. In addition, lower stresses extend the durability of the valve. However, the trileaflet valve geometry has also disadvantages, for instance, small peripheral streams or relatively low effective orifice area.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Acta of bioengineering and biomechanics
Acta of bioengineering and biomechanics BIOPHYSICS-ENGINEERING, BIOMEDICAL
CiteScore
2.10
自引率
10.00%
发文量
0
期刊介绍: Acta of Bioengineering and Biomechanics is a platform allowing presentation of investigations results, exchange of ideas and experiences among researchers with technical and medical background. Papers published in Acta of Bioengineering and Biomechanics may cover a wide range of topics in biomechanics, including, but not limited to: Tissue Biomechanics, Orthopedic Biomechanics, Biomaterials, Sport Biomechanics.
期刊最新文献
Characterization of biomaterials with reference to biocompatibility dedicated for patient-specific finger implants Dynamic-passive correction of hallux valgus and associated static foot deformities Quantitative evaluation of stereoscopic augmented reality visualization using an optical see-through head-mounted display Analysis of Muscle Activity During Rowing Stroke Phases Experimental research of energy absorbing structures within helmet samples made with the additive manufacturing method - preliminary study
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1