白唇树蝮的基因组组装和注释。

GigaByte (Hong Kong, China) Pub Date : 2024-01-25 eCollection Date: 2024-01-01 DOI:10.46471/gigabyte.106
Xiaotong Niu, Yakui Lv, Jin Chen, Yueheng Feng, Yilin Cui, Haorong Lu, Hui Liu
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引用次数: 0

摘要

白唇蝮蛇(Trimeresurus albolabris)又称白唇蝮或白唇树蝰,是一种分布于东南亚的剧毒蛇类,也是许多蛇咬伤病例的病因。在这项研究中,我们报告了首次通过新一代测序从中国云南蒙自采集的标本中获得的白唇蝮蛇全基因组组装结果。经过基因组测序和组装,这只雄性白纹背天牛的基因组长度为 1.51 Gb,重复元素含量为 38.42%。利用该基因组共鉴定出 21,695 个基因,其中 99.17% 的基因可通过基因功能数据库进行注释。我们的基因组组装和注释过程通过系统发生树进行了验证,系统发生树包括六个物种,重点关注核基因组的单拷贝基因。这项研究将有助于今后对Trimeresurus生物学和蛇毒遗传基础的研究。
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The genome assembly and annotation of the white-lipped tree pit viper Trimeresurus albolabris.

Trimeresurus albolabris, also known as the white-lipped pit viper or white-lipped tree viper, is a highly venomous snake distributed across Southeast Asia and the cause of many snakebite cases. In this study, we report the first whole genome assembly of T. albolabris obtained with next-generation sequencing from a specimen collected in Mengzi, Yunnan, China. After genome sequencing and assembly, the genome of this male T. albolabris individual was 1.51 Gb in length and included 38.42% repeat-element content. Using this genome, 21,695 genes were identified, and 99.17% of genes could be annotated using gene functional databases. Our genome assembly and annotation process was validated using a phylogenetic tree, which included six species and focused on single-copy genes of nuclear genomes. This research will contribute to future studies on Trimeresurus biology and the genetic basis of snake venom.

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来源期刊
CiteScore
2.60
自引率
0.00%
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审稿时长
5 weeks
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