意外骨关节炎:兔子的风险因素、发病率和临床证据

Fatima Bagha, Emma Keeble
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摘要

这项回顾性队列研究的目的是评估由兽医护理的兔子群体中阑尾骨关节炎的患病率、风险因素和临床症状水平。研究人员评估了 311 只兔子在 4 年内因各种原因接受的计算机断层扫描报告,以确定是否有附关节骨关节炎的记录证据以及受影响的关节。调查的风险因素包括年龄、体重、身体状况、品种、性别和绝育情况。对于有证据表明患有骨关节炎的兔子,还检查了其临床记录,以评估临床症状是否明显。在 311 份计算机断层扫描报告中,有 61 份(19.6%)描述了骨关节炎的证据。最常见的受影响关节是肘关节和跗关节。性别、身体状况和男性的中性状况与骨关节炎之间没有明显的关系。女性年龄越大、体重越重和中性与骨关节炎之间的关系有统计学意义。在 61 只有计算机断层扫描骨关节炎证据的兔子中,只有 9 只(14.8%)在临床记录中记录了骨关节炎的临床症状。根据这项研究的结果,我们可以得出这样的结论:兔子的年龄和体重越大,以及雌性绝育状态越好,患附着性骨关节炎的风险就越高,但影像学上的变化与临床上明显的疾病之间的关系可能很差。
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Incidental osteoarthritis: risk factors, prevalence and clinical evidence in rabbits
The objective of this retrospective cohort study was to evaluate the prevalence, risk factors and level of clinically apparent disease associated with appendicular osteoarthritis in a population of rabbits under veterinary care. Computed tomography reports of 311 rabbits taken for any reason over a 4-year period were evaluated for recorded evidence of appendicular osteoarthritis and the joint(s) affected. Risk factors including age, weight, body condition, breed, sex and neuter status were investigated. In rabbits with evidence of osteoarthritis, clinical notes were examined to evaluate if the condition was clinically apparent. Out of 311 computed tomography reports, 61 described evidence of osteoarthritis (19.6%). The most common joints affected were the elbow and stifle. No significant relationship between sex, body condition and neuter status in males and presence of osteoarthritis was found. A statistically significant relationship between greater age, greater weight and neuter status in females and the presence of osteoarthritis was found. Only 9 out of 61 (14.8%) of the rabbits with computed tomography evidence of osteoarthritis had clinical signs of osteoarthritis recorded in the clinical notes. Following the results of this study, it may be concluded that greater age and weight, as well as female neuter status, are related to increased risk of appendicular osteoarthritis in rabbits, but changes on imaging may relate poorly to clinically apparent disease.
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