{"title":"上呼吸道的上皮干细胞和祖细胞。","authors":"Maral J. Rouhani , Sam M. Janes , Carla F. Kim","doi":"10.1016/j.cdev.2024.203905","DOIUrl":null,"url":null,"abstract":"<div><p>The upper airway acts as a conduit for the passage of air to the respiratory system and is implicated in several chronic diseases. Whilst the cell biology of the distal respiratory system has been described in great detail, less is known about the proximal upper airway. In this review, we describe the relevant anatomy of the upper airway and discuss the literature detailing the identification and roles of the progenitor cells of these regions.</p></div>","PeriodicalId":36123,"journal":{"name":"Cells and Development","volume":"177 ","pages":"Article 203905"},"PeriodicalIF":3.9000,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667290124000068/pdfft?md5=80c073a8067ce7d4b678ed2e5eb0918d&pid=1-s2.0-S2667290124000068-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Epithelial stem and progenitor cells of the upper airway\",\"authors\":\"Maral J. Rouhani , Sam M. Janes , Carla F. Kim\",\"doi\":\"10.1016/j.cdev.2024.203905\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The upper airway acts as a conduit for the passage of air to the respiratory system and is implicated in several chronic diseases. Whilst the cell biology of the distal respiratory system has been described in great detail, less is known about the proximal upper airway. In this review, we describe the relevant anatomy of the upper airway and discuss the literature detailing the identification and roles of the progenitor cells of these regions.</p></div>\",\"PeriodicalId\":36123,\"journal\":{\"name\":\"Cells and Development\",\"volume\":\"177 \",\"pages\":\"Article 203905\"},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2024-02-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2667290124000068/pdfft?md5=80c073a8067ce7d4b678ed2e5eb0918d&pid=1-s2.0-S2667290124000068-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cells and Development\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2667290124000068\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Biochemistry, Genetics and Molecular Biology\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cells and Development","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2667290124000068","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Biochemistry, Genetics and Molecular Biology","Score":null,"Total":0}
Epithelial stem and progenitor cells of the upper airway
The upper airway acts as a conduit for the passage of air to the respiratory system and is implicated in several chronic diseases. Whilst the cell biology of the distal respiratory system has been described in great detail, less is known about the proximal upper airway. In this review, we describe the relevant anatomy of the upper airway and discuss the literature detailing the identification and roles of the progenitor cells of these regions.