成人炎症性肠病患者的健康维护策略

Kavita Sethi, Karishma Sethi-Arora, Jimmy K. Limdi
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摘要

炎症性肠病(IBD)和相关的免疫调节药物疗法与可避免的并发症风险增加有关,包括疫苗可预防的机会性感染、癌症、骨质疏松症、焦虑症和精神疾病。随着治疗手段的不断扩大,我们需要对这些并发症以及降低这些患者发病率所需的预防方法有深入的了解。本综述旨在总结适当的健康维护策略,包括在免疫抑制的背景下进行适当的治疗前感染筛查和疫苗接种建议,并促进及时筛查恶性肿瘤、骨质疏松症和心理疾病。明确的沟通、个性化的行动计划以及消化内科医生和初级保健医生之间的凝聚力对于优化 IBD 患者的健康维护至关重要。
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Health maintenance strategies in adults with inflammatory bowel disease

The Inflammatory Bowel Diseases (IBD) and associated immune-modulating pharmacotherapies are associated with an increased risk of avoidable complications, including vaccine-preventable opportunistic infections, cancers, osteoporosis, anxiety, and mental health disorders. The expanding therapeutic armamentarium requires a critical understanding of such complications and the preventative approaches required to reduce morbidity in these patients. Despite this, primary prevention strategies are often not prioritised in IBD patients.

This review aims to summarise appropriate health maintenance strategies, including appropriate pre-treatment infection screening and vaccination recommendations within the context of immunosuppression, and promotes timely screening for malignancies, osteoporosis, and psychological conditions. Clear communication, individualised action plans and cohesion between gastroenterologists and primary care physicians is crucial in optimising health maintenance in IBD patients.

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