管理澳大利亚蛙类糜烂性真菌病的进展:维多利亚州 Gradarius Firmus

IF 8.7 1区 农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE Annual Review of Animal Biosciences Pub Date : 2024-02-15 DOI:10.1146/annurev-animal-021122-100823
Lee Berger, Lee F Skerratt, Tiffany A Kosch, Laura A Brannelly, Rebecca J Webb, Anthony W Waddle
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引用次数: 0

摘要

自发现糜烂丝虫病以来的 25 年间,世界各地的研究工作积累了丰富的知识,可用于改善管理。在短期内挽救种群和/或使其恢复的策略包括人工繁殖、移入疾病庇护所、从抗病种群中移出、无病隔离、保留与以前栖息地相连的疾病庇护所,而抗真菌治疗则降低了野外死亡率。提高宿主抵抗力是许多正在开发的战略的目标,包括疫苗接种和有针对性的基因干预。病原体导向战略可能更具挑战性,但具有广泛的适用性。在继续寻找 "银弹 "解决方案的同时,我们应该重视有针对性的局部干预措施,以阻止物种灭绝,并为抗药性的进化或新型解决方案的开发争取时间。对于大多数入侵物种和传染病,我们需要接受持续管理是必要的。对于持续减少的物种,积极部署和评估有前景的干预措施比放手不管、不造成伤害的方法更有效,因为后者很可能导致物种进一步灭绝。
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Advances in Managing Chytridiomycosis for Australian Frogs: Gradarius Firmus Victoria.

Extensive knowledge gains from research worldwide over the 25 years since the discovery of chytridiomycosis can be used for improved management. Strategies that have saved populations in the short term and/or enabled recovery include captive breeding, translocation into disease refugia, translocation from resistant populations, disease-free exclosures, and preservation of disease refuges with connectivity to previous habitat, while antifungal treatments have reduced mortality rates in the wild. Increasing host resistance is the goal of many strategies under development, including vaccination and targeted genetic interventions. Pathogen-directed strategies may be more challenging but would have broad applicability. While the search for the silver bullet solution continues, we should value targeted local interventions that stop extinction and buy time for evolution of resistance or development of novel solutions. As for most invasive species and infectious diseases, we need to accept that ongoing management is necessary. For species continuing to decline, proactive deployment and assessment of promising interventions are more valid than a hands-off, do-no-harm approach that will likely allow further extinctions.

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来源期刊
Annual Review of Animal Biosciences
Annual Review of Animal Biosciences BIOTECHNOLOGY & APPLIED MICROBIOLOGY-ZOOLOGY
CiteScore
21.30
自引率
0.80%
发文量
31
期刊介绍: The Annual Review of Animal Biosciences is primarily dedicated to the fields of biotechnology, genetics, genomics, and breeding, with a special focus on veterinary medicine. This includes veterinary pathobiology, infectious diseases and vaccine development, and conservation and zoo biology. The publication aims to address the needs of scientists studying both wild and domesticated animal species, veterinarians, conservation biologists, and geneticists.
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