对术前存在胃食管反流的病态肥胖患者进行腹腔镜 Toupet-Sleeve 胃切除术:一项为期 4 年的随访队列研究。

Pub Date : 2024-10-01 Epub Date: 2024-02-21 DOI:10.1080/00015458.2024.2320504
Hauters Philippe, Granjean Steven, Stefanescu Iulia, Jacqmin Geoffrey, Gerard Mickaël, van Vyve Etienne
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引用次数: 0

摘要

目的:评估术前合并胃食管反流病(GERD)的病态肥胖患者行Toupet-Sleeve(TS)胃切除术后的4年预后:研究组由2017年8月至2019年2月期间连续接受手术的19名患者组成。其中男性5人,女性14人,平均体重指数(BMI)为43±5 kg/m2,平均年龄为42±15岁。研究人员对数据库进行了回顾性分析,并对未接受门诊随访的患者进行了电话访谈。研究的主要终点是体重减轻和手术成功率,即无需转院和EWL%>50%。胃食管反流病的缓解是次要终点:没有患者失去随访机会。随访一年后体重达到最低点:平均体重指数(BMI)为 32 ± 5 kg/m2,%EWL 为 61 ± 21%,%TWL 为 24 ± 7%。此后,我们观察到体重随着时间的推移逐渐恢复。平均随访时间为 51 ± 6 个月,平均体重指数为 36 ± 8 kg/m2,%EWL 为 43 ± 35%,%TWL 为 16 ± 12%。两名患者因吞咽困难、眼底扩张或体重减轻不足而转为其他减肥手术。总体手术成功率为 32%(6/19)。88%(15/17)的非转归患者在未接受任何 PPI 治疗的情况下,胃食管反流病得到了缓解:根据我们的经验,在 4 年的随访中,TS 与巨大的转归风险、适度的体重减轻和较低的手术成功率有关。
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Laparoscopic Toupet-Sleeve gastrectomy in morbid obese patients with preoperative gastro-esophageal reflux: a 4-year follow-up cohort study.

Aim: To assess the 4-year outcomes after Toupet-Sleeve (TS) gastrectomy in morbid obese patients with concomitant preoperative gastro-esophageal reflux disease (GERD).

Material and methods: The study group consisted of 19 consecutive patients operated on between August 2017 and February 2019. There were 5 men and 14 women with a mean body mass index (BMI) of 43 ± 5 kg/m2 and a mean age of 42 ± 15 years. A retrospective analysis of database and telephone interview of patients who defaulted clinic follow-up was conducted. The main study end-points were weight loss and success of surgery, defined as no need for conversion and %EWL > 50%. Resolution of GERD was a secondary end-point.

Results: No patient was lost for follow-up. Nadir weight loss was reached after a follow-up of one year: mean BMI was 32 ± 5 kg/m2, %EWL 61 ± 21% and %TWL 24 ± 7%. Thereafter, we observed a progressive weight regain over time. With a mean follow-up of 51 ± 6 months, mean BMI was 36 ± 8 kg/m2, %EWL 43 ± 35% and %TWL 16 ± 12%. Two patients were converted to another bariatric procedure because of dysphagia and fundus dilatation or because of insufficient weight loss. The overall surgical success rate was 32% (6/19). Resolution of GERD without any PPI treatment was noted in 88% (15/17) of the non-converted patients.

Conclusion: In our experience, with a 4-year follow-up, TS is associated with a significant risk of conversion, a moderate weight loss and a poor surgical success rate.

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