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Adrenal tumor bleeding versus ruptured abdominal aortic aneurysm: a diagnostic dilemma in retroperitoneal hemorrhage. 肾上腺肿瘤出血与腹主动脉瘤破裂:腹膜后出血的诊断困境。
IF 0.8 4区 医学 Q4 SURGERY Pub Date : 2026-01-28 DOI: 10.1080/00015458.2026.2619484
Maud A M Vesseur, Ine Rochus, Lee Bouwman, Ozan Yazar

Background: Retroperitoneal hemorrhage is a life-threatening entity that can result from a range of etiologies. Rupture of an abdominal aortic aneurysm (AAA) is the most common vascular emergency associated with high morbidity and mortality. However, not all retroperitoneal hemorrhages result from this vascular emergency. Adrenal hemorrhage, though rare, represents an important, often under-recognized and potentially fatal alternative diagnosis. The diagnostic challenge is further compounded when such adrenal pathology occurs in the presence of a concurrent AAA, as overlapping clinical and radiologic features can obscure the true source of bleeding. This coexistence can lead to misdiagnosis, delays in appropriate treatment, and complex decision-making in the acute care setting.

Case report: A man in his 70s presented with hemodynamic collapse and right-sided flank pain, initially raising concern for a ruptured abdominal aortic aneurysm (AAA). Imaging revealed both an infrarenal AAA and a large retroperitoneal mass consistent with a hemorrhaging adrenal lesion. Due to diagnostic uncertainty and persistent hemodynamic instability, the patient underwent emergency endovascular aortic repair (EVAR) followed by selective arterial embolization of the adrenal lesion. Postoperative recovery was favorable, with resolution of hemodynamic instability and planned delayed adrenalectomy.

Conclusion: This case report illustrates the diagnostic complexity and clinical challenge posed by simultaneous adrenal hemorrhage and AAA. Adrenal tumors can cause life-threatening retroperitoneal hemorrhage. Timely recognition via high-resolution imaging and a flexible interventional approach tailored to the evolving clinical picture are key to successful management. Clinicians should remain vigilant for alternative bleeding sources, even in the context of known vascular disease.

背景:腹膜后出血是一种危及生命的疾病,其病因多种多样。腹主动脉瘤破裂(AAA)是最常见的血管急症,具有高发病率和死亡率。然而,并不是所有的腹膜后出血都是由这种血管急症引起的。肾上腺出血,虽然罕见,代表了一个重要的,经常被低估和潜在致命的替代诊断。当这种肾上腺病理同时出现AAA时,诊断难度进一步增加,因为重叠的临床和放射学特征会模糊出血的真正来源。这种共存可能导致误诊,延误适当的治疗,并在急性护理设置复杂的决策。病例报告:一名70多岁的男性表现为血液动力学塌陷和右侧腹部疼痛,最初引起了对腹主动脉瘤破裂(AAA)的关注。影像学显示有一个肾下AAA和一个大的腹膜后肿块,与出血性肾上腺病变一致。由于诊断不确定和持续的血流动力学不稳定,患者接受了紧急血管内主动脉修复术(EVAR),随后选择性动脉栓塞治疗肾上腺病变。术后恢复良好,血流动力学不稳定和计划延迟肾上腺切除术得到解决。结论:本病例报告说明了并发肾上腺出血和AAA的诊断复杂性和临床挑战,肾上腺肿瘤可导致危及生命的腹膜后出血。通过高分辨率成像及时识别和灵活的介入方法量身定制的不断变化的临床图像是成功管理的关键。临床医生应该对其他出血来源保持警惕,即使在已知血管疾病的情况下。
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引用次数: 0
Resection of intracardiac tumors in infants. 婴儿心内肿瘤的切除。
IF 0.8 4区 医学 Q4 SURGERY Pub Date : 2026-01-28 DOI: 10.1080/00015458.2026.2616127
Nobels Sarah, Thierry Bové

Intracardiac tumors in children are rare, mostly benign, and occasionally related to genetic syndromes (p.e. tuberous sclerosis or Gorlin syndrome). Echocardiography, CT and MRI are the golden standard for diagnosis and surgical removal is indicated when the tumor is symptomatic by hemodynamic interference. We present 4 cases of infants with an intracardiac tumor, all of them needing surgical removal.

儿童心内肿瘤是罕见的,大多是良性的,偶尔与遗传综合征(如结节性硬化症或Gorlin综合征)有关。超声心动图,CT和MRI是诊断的金标准,当肿瘤有血流动力学干扰症状时,应手术切除。我们报告了4例婴儿心脏内肿瘤,他们都需要手术切除。
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引用次数: 0
Plastic surgery in 19th century in Greece. The important role of professor Theodoros Aretaios (1829-1893). 19世纪希腊的整形手术。Theodoros Aretaios教授(1829-1893)的重要作用。
IF 0.8 4区 医学 Q4 SURGERY Pub Date : 2026-01-19 DOI: 10.1080/00015458.2026.2617870
Pavlos Lytsikas-Sarlis, Konstantinos Laios, Constantinos G Zografos, Christina Nikolaou, Georgios Tsakotos, Konstantinos G Apostolou, Tsoucalas Gregory, Dimitrios Schizas

Aim: To highlight the practice of plastic surgery in Greece during the nineteenth century, its possibilities, limits, and novelties, which mark the beginning of Greek plastic surgery.

Materials and methods: Study of nineteenth century Greek medical literature and medical archive kept today in National Library of Greece, which are for the first time brought to light.

Results: Greek physicians tried to use skin grafts in order to reconstruct facial trauma, deformities, and treat oncological patients. Greek physicians kept up to date and followed the international achievements in plastic surgery at the time.

Conclusion: The most prominent figure of Greek surgery during the nineteenth century, Professor Theodoros Aretaios (1829-1893), played a leading role in the development of Greek plastic surgery.

目的:突出19世纪希腊整形手术的实践,它的可能性,局限性和新奇性,这标志着希腊整形手术的开始。材料和方法:研究19世纪希腊医学文献和保存在希腊国家图书馆的医学档案,这是第一次曝光。结果:希腊医生尝试使用皮肤移植来重建面部创伤、畸形和治疗肿瘤患者。希腊医生紧跟当时国际整形外科的最新发展。结论:19世纪希腊外科最杰出的人物是Theodoros Aretaios教授(1829-1893),他在希腊整形外科的发展中发挥了主导作用。
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引用次数: 0
Gastric metastases from invasive lobular carcinoma of the breast: case report and literature review. 浸润性乳腺小叶癌胃转移:病例报告及文献复习。
IF 0.8 4区 医学 Q4 SURGERY Pub Date : 2026-01-19 DOI: 10.1080/00015458.2026.2615918
João Ricardo Serra, Elisabete do Vale Campos, Miguel Andrade de Almeida, Fabiana Silva de Sousa, Raquel Portugal, António Pereira, Silvestre Carneiro, José Barbosa

Background: Gastric metastases from breast cancer are rare clinical entities that often mimic primary gastric malignancies, leading to diagnostic delay. Invasive lobular carcinoma (ILC), due to its diffuse growth pattern and loss of E-cadherin expression, demonstrates a higher propensity for metastasizes to the gastrointestinal tract.

Methods: Clinical data for this study were retrospectively collected from the hospital's electronic clinical program.

Results: The authors report the case of a 42-year-old woman with bilateral stage IV ILC who subsequently developed bilateral ovarian and gastric metastases. We discuss the clinical, histopathologic, and imaging features, with emphasis on differential diagnosis and therapeutic strategies considering current evidence.

Conclusion: This case highlights the diagnostic challenge of gastric metastases from ILC, which may present many years after the initial diagnosis. Definitive diagnosis requires immunohistochemistry to distinguish metastatic breast carcinoma from primary gastric carcinoma. Systemic therapy remains the mainstay of treatment, while surgical intervention should be reserved for selected palliative indications. Increased awareness of this rare manifestation is crucial to avoid misdiagnosis and optimize multidisciplinary management.

乳腺癌的胃转移是罕见的临床实体,通常模仿原发性胃恶性肿瘤,导致诊断延迟。侵袭性小叶癌(ILC),由于其弥漫性生长模式和E-cadherin表达的缺失,显示出更高的胃肠道转移倾向。作者报告了一例42岁女性双侧IV期ILC,随后发展为双侧卵巢和胃转移。我们讨论临床,组织病理学和影像学特征,重点是鉴别诊断和治疗策略考虑到目前的证据。这个病例强调了ILC胃转移的诊断挑战,它可能在最初诊断多年后出现。明确的诊断需要免疫组化来区分转移性乳腺癌和原发性胃癌。全身治疗仍然是治疗的主要手段,而手术干预应保留用于选定的姑息指征。提高对这种罕见表现的认识对于避免误诊和优化多学科管理至关重要。
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引用次数: 0
A systematic review and meta-analysis: robotic versus laparoscopic hiatal hernia repair, is there a difference in Clavien Dindo score? 一项系统回顾和meta分析:机器人与腹腔镜裂孔疝修补术,Clavien Dindo评分有差异吗?
IF 0.8 4区 医学 Q4 SURGERY Pub Date : 2026-01-03 DOI: 10.1080/00015458.2025.2611452
A Mathys, H Vanommeslaeghe, Y Van Nieuwenhove, E Van Daele

Background: Laparoscopic hiatal hernia repair is considered the golden standard. Since its entrance in the mid-'00s, robotic surgery has been available in every modern operating center. The aim of this systematic review and meta-analyses is to compare laparoscopic versus robotic surgical hiatal hernia repair regarding clinically relevant postoperative complications, using the Clavien Dindo score 3.

Methods: After registration in PROSPERO, a literature review was performed following the PRISMA flow diagram, resulting in eleven studies. Their quality was assessed using the Newcastle-Ottowa scale. Risk of bias was assessed using the ROBINS-I tool. Statistical analysis was performed using Python. The primary outcome was Clavien Dindo score 3, the secondary outcomes were mortality, intraoperative complications, postoperative complications, length of stay and operation time.

Results: Eleven studies (182.467 patients in total, 12.056 robotic surgical repairs) were analyzed. The meta-analysis showed no statistically significant result between CD score 3 (OR = 0,68 (95% CI 0,27 - 1,72)). From the investigated secondary outcomes, only intraoperative complications showed a significant difference favoring robotic repair (OR = 0,41 (95% CI 0,22 - 0,76) and p-value = 0,005).

Conclusion: Robotic hiatal hernia repair shows less intraoperative complications in comparison to laparoscopic repair. With the current available literature, no difference in Clavien Dindo score 3 is seen. To investigate the full potential of robotic surgery, prospective studies should be performed with surgeons who have passed their learning curve. Subgroup analyses regarding giant hiatal hernia and redo surgery should be performed. A uniform definition of 'giant' hiatal hernia is needed.

背景腹腔镜裂孔疝修补被认为是金标准。自2000年代中期问世以来,每个现代手术中心都可以使用机器人手术。本系统综述和meta分析的目的是使用Clavien Dindo评分3分,比较腹腔镜与机器人手术裂孔疝修补术在临床相关术后并发症方面的差异。方法在PROSPERO登记后,按照PRISMA流程图进行文献回顾,共纳入11项研究。他们的质量是用纽卡斯尔-渥太华量表评估的。使用ROBINS-I工具评估偏倚风险。使用Python进行统计分析。主要观察指标Clavien Dindo评分为3分,次要观察指标为死亡率、术中并发症、术后并发症、住院时间和手术时间。结果共分析11项研究(共182.467例患者,12.056例机器人手术修复)。meta分析显示CD评分3分之间无统计学差异(OR = 0.68 (95% CI 0.27 - 1.72))。从调查的次要结果来看,只有术中并发症表现出有利于机器人修复的显著差异(OR = 0.41 (95% CI 0.22 - 0.76), p值= 0.005)。结论机器人修补裂孔疝术中并发症比腹腔镜修补术少。根据现有文献,Clavien Dindo评分3没有差异。为了调查机器人手术的全部潜力,前瞻性研究应该与已经通过学习曲线的外科医生一起进行。对于巨大裂孔疝和重做手术应进行亚组分析。“巨大”裂孔疝需要一个统一的定义。
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引用次数: 0
Posterior tibial artery pseudoaneurysm after titanium elastic nailing for tibial shaft fracture in a 7-year-old boy. 钛弹性钉治疗7岁男童胫骨干骨折后胫骨后动脉假性动脉瘤一例。
IF 0.8 4区 医学 Q4 SURGERY Pub Date : 2025-12-20 DOI: 10.1080/00015458.2025.2605480
Dorotea Sinjeri, Dino Papeš, Josip Lovaković, Anko Antabak

Background: Flexible intramedullary nailing is a minimally invasive method used for pediatric tibial shaft fractures stabilization.

Case presentation: A seven-year-old boy sustained a midshaft oblique tibial fracture due to a fall from one meter height and was treated by closed reduction and intramedullary nailing. On the first postoperative day, a swelling of the proximal half of the lower leg occurred and progressed to compartment syndrome. The lower leg was edematous, firm and painful on palpation, and the pain at rest was out of proportion to injury. CT angiography showed a posterior tibial artery pseudoaneurysm and no signs of deep venous thrombosis. He was successfully treated by pseudoaneurysm evacuation and saphenous vein patch repair of the posterior tibial artery. Postoperative course was uneventful.

Conclusion: Vascular complications after flexible intramedullary nailing in children are rare and require early recognition. In this case, treatment by open surgical technique was successful.

背景:弹性髓内钉是一种用于小儿胫骨干骨折稳定的微创方法。病例介绍:一名7岁男孩因从1米高处坠落导致胫骨中轴斜骨折,采用闭合复位和髓内钉治疗。术后第一天,下肢近端出现肿胀并发展为筋膜室综合征。下肢触诊肿胀、僵硬、疼痛,静息时疼痛与损伤不成比例。CT血管造影显示胫骨后动脉假性动脉瘤,未见深静脉血栓形成征象。假性动脉瘤清除术及胫后动脉隐静脉修补术成功治疗。术后过程顺利。结论:儿童弹性髓内钉术后血管并发症罕见,需及早发现。在这个病例中,开放手术技术的治疗是成功的。
{"title":"Posterior tibial artery pseudoaneurysm after titanium elastic nailing for tibial shaft fracture in a 7-year-old boy.","authors":"Dorotea Sinjeri, Dino Papeš, Josip Lovaković, Anko Antabak","doi":"10.1080/00015458.2025.2605480","DOIUrl":"10.1080/00015458.2025.2605480","url":null,"abstract":"<p><strong>Background: </strong>Flexible intramedullary nailing is a minimally invasive method used for pediatric tibial shaft fractures stabilization.</p><p><strong>Case presentation: </strong>A seven-year-old boy sustained a midshaft oblique tibial fracture due to a fall from one meter height and was treated by closed reduction and intramedullary nailing. On the first postoperative day, a swelling of the proximal half of the lower leg occurred and progressed to compartment syndrome. The lower leg was edematous, firm and painful on palpation, and the pain at rest was out of proportion to injury. CT angiography showed a posterior tibial artery pseudoaneurysm and no signs of deep venous thrombosis. He was successfully treated by pseudoaneurysm evacuation and saphenous vein patch repair of the posterior tibial artery. Postoperative course was uneventful.</p><p><strong>Conclusion: </strong>Vascular complications after flexible intramedullary nailing in children are rare and require early recognition. In this case, treatment by open surgical technique was successful.</p>","PeriodicalId":6935,"journal":{"name":"Acta Chirurgica Belgica","volume":" ","pages":"1-3"},"PeriodicalIF":0.8,"publicationDate":"2025-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145766745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent hypertrophic pyloric stenosis, diagnosis and early surgery: a comprehensive review. 复发性肥厚性幽门狭窄,诊断和早期手术:全面回顾。
IF 0.8 4区 医学 Q4 SURGERY Pub Date : 2025-12-18 DOI: 10.1080/00015458.2025.2586864
Martin Schils, Haidar Houmani, Kalliroi Kotilea, Corina Zamfir, Anna Poupalou, Helena Reusens

Background: Recurrent pyloric stenosis (RPS) is a very rare condition that occurs after an initially successful pyloromyotomy for hypertrophic pyloric stenosis. Over the last decade, the number of reported cases of recurrent pyloric stenosis has increased considerably. Given the rarity of this condition and the paucity of literature on the subject, there is a certain diagnostic difficulty, particularly at ultrasound level, where it is difficult to differentiate a true recurrence of pyloric stenosis from an initial incomplete pyloromyotomy.

Methods: A systematic literature review was performed to characterize the diagnosis of RPS and to report on all cases previously described in literature.

Results: We identified a total of 15 patients (median age of 19 days at first pyloromyotomy; average of 31 days of symptom-free interval before RPS; 66.7% male). Eleven cases fulfilled the 3 Kuckelman criteria for RPS (weight gain, 3 weeks resolution of symptoms, restenosis on imaging). The length of the pylorus on ultrasound appears to increase or remain above 18 mm for RPS, where normally it should decrease immediately after pyloromyotomy. RPS seems to occur more frequently when the first pyloromyotomy is performed at an early age.

Conclusion: Hypertrophy of the pyloric muscle is a progressive entity, and if operated upon too early can favor recurrence. The diagnosis of a RPS can be made through the combination of clinical criteria and ultrasound, specifically length measurements of the pylorus. Additional studies need to be performed to confirm our findings and to define strategies to reduce risks for RPS.

背景:复发性幽门狭窄(RPS)是一种非常罕见的情况,发生在最初成功的幽门切开术治疗肥厚性幽门狭窄。在过去的十年中,报告的复发性幽门狭窄的病例数量大大增加。鉴于这种情况的罕见性和关于该主题的文献的缺乏,存在一定的诊断困难,特别是在超声水平上,很难区分真正的幽门狭窄复发和最初的不完全幽门切开术。方法:进行系统的文献回顾,以确定RPS的诊断特征,并报告先前文献中描述的所有病例。结果:我们共确定了15例患者(首次幽门肌切开术时的中位年龄为19天;RPS前的平均无症状间隔为31天;66.7%为男性)。11例患者符合RPS的3个Kuckelman标准(体重增加,症状缓解3周,影像学再狭窄)。超声显示幽门长度在RPS中增加或保持在18mm以上,而在正常情况下,幽门切开术后幽门长度应立即减小。当第一次幽门肌切开术在早期进行时,RPS似乎更常发生。结论:幽门肌肥大是一种进行性疾病,过早手术易复发。RPS的诊断可以通过结合临床标准和超声,特别是幽门长度测量来进行。需要进行更多的研究来证实我们的发现,并确定降低RPS风险的策略。
{"title":"Recurrent hypertrophic pyloric stenosis, diagnosis and early surgery: a comprehensive review.","authors":"Martin Schils, Haidar Houmani, Kalliroi Kotilea, Corina Zamfir, Anna Poupalou, Helena Reusens","doi":"10.1080/00015458.2025.2586864","DOIUrl":"10.1080/00015458.2025.2586864","url":null,"abstract":"<p><strong>Background: </strong>Recurrent pyloric stenosis (RPS) is a very rare condition that occurs after an initially successful pyloromyotomy for hypertrophic pyloric stenosis. Over the last decade, the number of reported cases of recurrent pyloric stenosis has increased considerably. Given the rarity of this condition and the paucity of literature on the subject, there is a certain diagnostic difficulty, particularly at ultrasound level, where it is difficult to differentiate a true recurrence of pyloric stenosis from an initial incomplete pyloromyotomy.</p><p><strong>Methods: </strong>A systematic literature review was performed to characterize the diagnosis of RPS and to report on all cases previously described in literature.</p><p><strong>Results: </strong>We identified a total of 15 patients (median age of 19 days at first pyloromyotomy; average of 31 days of symptom-free interval before RPS; 66.7% male). Eleven cases fulfilled the 3 Kuckelman criteria for RPS (weight gain, 3 weeks resolution of symptoms, restenosis on imaging). The length of the pylorus on ultrasound appears to increase or remain above 18 mm for RPS, where normally it should decrease immediately after pyloromyotomy. RPS seems to occur more frequently when the first pyloromyotomy is performed at an early age.</p><p><strong>Conclusion: </strong>Hypertrophy of the pyloric muscle is a progressive entity, and if operated upon too early can favor recurrence. The diagnosis of a RPS can be made through the combination of clinical criteria and ultrasound, specifically length measurements of the pylorus. Additional studies need to be performed to confirm our findings and to define strategies to reduce risks for RPS.</p>","PeriodicalId":6935,"journal":{"name":"Acta Chirurgica Belgica","volume":" ","pages":"1-6"},"PeriodicalIF":0.8,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145450593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rethinking 'extreme' cytoreductive surgery in malignant peritoneal mesothelioma. 恶性腹膜间皮瘤“极端”细胞减少手术的再思考。
IF 0.8 4区 医学 Q4 SURGERY Pub Date : 2025-12-14 DOI: 10.1080/00015458.2025.2604539
Semra Demirli Atici, Aras Emre Canda, Mustafa Cem Terzi
{"title":"Rethinking 'extreme' cytoreductive surgery in malignant peritoneal mesothelioma.","authors":"Semra Demirli Atici, Aras Emre Canda, Mustafa Cem Terzi","doi":"10.1080/00015458.2025.2604539","DOIUrl":"10.1080/00015458.2025.2604539","url":null,"abstract":"","PeriodicalId":6935,"journal":{"name":"Acta Chirurgica Belgica","volume":" ","pages":"1-2"},"PeriodicalIF":0.8,"publicationDate":"2025-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145740472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Joseph Maclise's (1815-1891) legacy to the surgical anatomy of the inguinal region. 约瑟夫·麦克利斯(1815-1891)对腹股沟外科解剖的贡献。
IF 0.8 4区 医学 Q4 SURGERY Pub Date : 2025-12-05 DOI: 10.1080/00015458.2025.2598566
A Moreno-Egea, C Moreno-Latorre, A Moreno-Latorre

Background. The work of the anatomist surgeon Joseph Maclise has been forgotten by history. His contributions are unknown to younger generations. This study aims to analyze his legacy, focusing on the surgical anatomy of hernias. Results. This is the first study to analyze Maclise's work from a surgical, rather than an artistic, perspective, focusing on the pathology of hernias. His life was marked by a lack of academic and/or institutional recognition. He was forgotten by the Royal College of Surgeons a decade before his death. He collaborated with Morton on his treatise on surgical anatomy. His work was fundamental to the training of surgeons for at least three decades and served as a bridge between two continents. In the field of hernias, he simplifies knowledge for surgeons, shows each type of hernia in anterior and posterior approaches, and describes the region as a single space where all hernias appear. Conclusion. Maclise was an exemplary Victorian surgeon who cultivated many fields of practice (surgical anatomy, comparative anatomy and naturalism, experimental anatomy and physiology, embryology, art and painting), committed to the advancement of science in his time. His surgical anatomy of hernias facilitated the visual understanding of this pathology for surgeons of several generations.

解剖外科医生约瑟夫·麦克利斯的工作已被历史遗忘。年轻一代不知道他的贡献。本研究旨在分析他的遗产,重点是疝气的外科解剖。这是第一个从外科而非艺术角度分析麦克利斯作品的研究,重点关注疝气的病理学。他一生的特点是缺乏学术和(或)机构的认可。他在去世前10年就被皇家外科医学院遗忘了。他与莫顿合作撰写了外科解剖学的专著。他的工作在至少30年的时间里对外科医生的培训至关重要,并在两个大陆之间架起了一座桥梁。在疝领域,他简化了外科医生的知识,展示了前后入路的每种类型的疝,并将该区域描述为所有疝出现的单一空间。麦克利斯是维多利亚时代外科医生的典范,他在许多领域都有实践(外科解剖学、比较解剖学和自然主义、实验解剖学和生理学、胚胎学、艺术和绘画),致力于他那个时代的科学进步。他对疝气的外科解剖促进了几代外科医生对这种病理的视觉理解。
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引用次数: 0
Evaluation of prognostic factors in patients undergoing surgery for colorectal cancer lung metastases. 结直肠癌肺转移手术患者预后因素的评价。
IF 0.8 4区 医学 Q4 SURGERY Pub Date : 2025-12-02 DOI: 10.1080/00015458.2025.2595325
Auréline Cousinne, Maarten Vander Kuylen, Maria Ruiz Patino, Matteo Cappello, Vincent Donckier, Youri Sokolow

Objectives: Lungs are the second most frequent site of colorectal cancer metastases. Complete resection of isolated lung metastases is recommended in the current guidelines because of the high long-term survival rate and low morbidity-mortality. The aim of this study is to determine prognostic factors for lung metastasectomy in order to better select patients who will benefit from surgical resection.

Methods: This single-center retrospective study is based on the medical data of patients operated for resection of colorectal lung metastases between 2004 and 2023.

Results: A total of 109 patients were selected, and four had to be excluded. The univariate analysis revealed factors influencing the survival: primary cancers that were metastatic at diagnosis, high preoperative CEA rate, the number and size of metastases, hilar lymph node involvement, invasion of the resection margins and poorly differentiated histological grade. A multivariate analysis including only the pre-operative factors was performed: CEA (p < 0.001), the size (p = 0.003) and number (p = 0.038) of metastases and the metastatic stage of the primary cancer at diagnosis (p = 0.052).

Conclusions: The 5-year survival rate in this study is 55%. Survival can be evaluated by four preoperative factors: CEA rate, size and number of metastases and metastatic status of the primary cancer. These factors can be combined to form a survival score, each factor being worth one point. Patients with a score of 0 have a 5-year survival of around 90%, while patients with a score of 3 have a 5-year survival of around 10%. This score could be used to select patients eligible for surgery.

目的:肺是结直肠癌第二常见的转移部位。由于长期生存率高,发病率-死亡率低,目前的指南推荐对孤立的肺转移瘤进行完全切除。本研究的目的是确定肺转移瘤切除术的预后因素,以便更好地选择将从手术切除中受益的患者。方法本研究为单中心回顾性研究,基于2004 - 2023年间行结直肠肺转移瘤切除术患者的医疗资料。结果109例患者入选,4例患者被排除。单因素分析显示影响生存率的因素为:诊断时转移的原发癌、术前CEA高、转移灶的数量和大小、肺门淋巴结受累性、切除边缘的浸润性和低分化组织学分级。仅包括术前因素的多因素分析:CEA (p)结论:本研究5年生存率为55%。生存率可通过术前4个因素评估:CEA率、转移灶大小和数量以及原发癌的转移状态。这些因素可以结合起来形成一个生存评分,每个因素值一分。0分患者的5年生存率约为90%,而3分患者的5年生存率约为10%。该评分可用于选择符合手术条件的患者。
{"title":"Evaluation of prognostic factors in patients undergoing surgery for colorectal cancer lung metastases.","authors":"Auréline Cousinne, Maarten Vander Kuylen, Maria Ruiz Patino, Matteo Cappello, Vincent Donckier, Youri Sokolow","doi":"10.1080/00015458.2025.2595325","DOIUrl":"10.1080/00015458.2025.2595325","url":null,"abstract":"<p><strong>Objectives: </strong>Lungs are the second most frequent site of colorectal cancer metastases. Complete resection of isolated lung metastases is recommended in the current guidelines because of the high long-term survival rate and low morbidity-mortality. The aim of this study is to determine prognostic factors for lung metastasectomy in order to better select patients who will benefit from surgical resection.</p><p><strong>Methods: </strong>This single-center retrospective study is based on the medical data of patients operated for resection of colorectal lung metastases between 2004 and 2023.</p><p><strong>Results: </strong>A total of 109 patients were selected, and four had to be excluded. The univariate analysis revealed factors influencing the survival: primary cancers that were metastatic at diagnosis, high preoperative CEA rate, the number and size of metastases, hilar lymph node involvement, invasion of the resection margins and poorly differentiated histological grade. A multivariate analysis including only the pre-operative factors was performed: CEA (<i>p</i> < 0.001), the size (<i>p</i> = 0.003) and number (<i>p</i> = 0.038) of metastases and the metastatic stage of the primary cancer at diagnosis (<i>p</i> = 0.052).</p><p><strong>Conclusions: </strong>The 5-year survival rate in this study is 55%. Survival can be evaluated by four preoperative factors: CEA rate, size and number of metastases and metastatic status of the primary cancer. These factors can be combined to form a survival score, each factor being worth one point. Patients with a score of 0 have a 5-year survival of around 90%, while patients with a score of 3 have a 5-year survival of around 10%. This score could be used to select patients eligible for surgery.</p>","PeriodicalId":6935,"journal":{"name":"Acta Chirurgica Belgica","volume":" ","pages":"1-8"},"PeriodicalIF":0.8,"publicationDate":"2025-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145627564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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