烧伤患者长期使用处方止痛药与疗效:烧伤模型系统国家数据库研究》。

IF 2.2 4区 医学 Q1 REHABILITATION American Journal of Physical Medicine & Rehabilitation Pub Date : 2024-09-01 Epub Date: 2024-02-12 DOI:10.1097/PHM.0000000000002448
Kevin Vu, Huan Deng, Brian Kelter, Lauren Shepler, Barclay Stewart, Steven Wolf, Samuel Mandell, Alyssa Bamer, Anupam Mehta, Lewis Kazis, Colleen Ryan, Jeffrey Schneider
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引用次数: 0

摘要

目的: 本研究试图探讨烧伤后长期使用止痛药物的情况及其与功能和社会心理影响的关系:本研究试图探讨烧伤后长期使用止痛药的情况及其与功能和社会心理结果的关系:这是一项利用烧伤模型系统国家纵向数据库进行的多中心回顾性队列研究。将 2015 年至 2021 年期间受伤的参与者分为两组,即在受伤后 12 个月内服用和未服用处方止痛药的两组。回归分析检验了止痛药使用情况与 12 个月后结果之间的关联,并对人口统计学、烧伤面积、住院时间、受伤前止痛药使用情况和就业状况进行了调整。结果包括:VR-12 身体和心理成分汇总得分(PCS 和 MCS)、患者报告结果测量信息系统(PROMIS-29)焦虑和抑郁得分、生活满意度量表(SWLS)以及就业状况:在分析的 358 名参与者中,处方止痛药的使用与 12 个月后的治疗效果较差有关:PCS(β=-7.11,p<0.001)、MCS(β=-6.01,p<0.001)、PROMIS-29 抑郁(β=4.88,p<0.001)和焦虑(β=6.16,p<0.001)。SWLS与止痛药的使用无明显关联(p = 0.069),而那些服用止痛药的人在12个月后就业的可能性降低了52%(p = 0.035):结论:在烧伤后 12 个月,处方止痛药的使用与身体、精神和就业状况的恶化有明显关系。
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Chronic Use of Prescription Pain Medication and Outcomes in Patients With Burn Injury: A Burn Model System National Database Study.

Objective: This study attempts to examine long-term pain medication usage after burn injury and its association with functional and psychosocial outcomes.

Design: This is a multicenter retrospective cohort study utilizing the Burn Model System National Longitudinal Database. Participants injured from 2015 to 2021 were divided into two groups, those taking and not taking prescription pain medication at 12 mos after injury. Regression analyses examined associations between pain medication use and outcomes at 12 mos, adjusting for demographics, burn size, length of hospital stay, and preinjury pain medication use and employment status. Outcomes included VR-12 Physical and Mental Component Summary scores Patient-Reported Outcomes Measurement Information System Anxiety and Depression scores, Satisfaction with Life Scale, and employment status.

Results: Of 358 participants analyzed, prescription pain medication use was associated with worse outcomes at 12 mos: Physical Component Summary (β = -7.11, P < 0.001), Mental Component Summary (β = -6.01, P < 0.001), and Patient-Reported Outcomes Measurement Information System Depression (β = 4.88, P < 0.001) and Anxiety (β = 6.16, P < 0.001). Satisfaction with Life Scale was not significantly associated with pain medication use ( P = 0.069) and those taking pain medication were 52% less likely to be employed at 12 mos ( P = 0.035).

Conclusions: There is a significant association between prescription pain medication use and worse physical, mental, and employment outcomes at 12 mos after burn injury.

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来源期刊
CiteScore
4.60
自引率
6.70%
发文量
423
审稿时长
1 months
期刊介绍: American Journal of Physical Medicine & Rehabilitation focuses on the practice, research and educational aspects of physical medicine and rehabilitation. Monthly issues keep physiatrists up-to-date on the optimal functional restoration of patients with disabilities, physical treatment of neuromuscular impairments, the development of new rehabilitative technologies, and the use of electrodiagnostic studies. The Journal publishes cutting-edge basic and clinical research, clinical case reports and in-depth topical reviews of interest to rehabilitation professionals. Topics include prevention, diagnosis, treatment, and rehabilitation of musculoskeletal conditions, brain injury, spinal cord injury, cardiopulmonary disease, trauma, acute and chronic pain, amputation, prosthetics and orthotics, mobility, gait, and pediatrics as well as areas related to education and administration. Other important areas of interest include cancer rehabilitation, aging, and exercise. The Journal has recently published a series of articles on the topic of outcomes research. This well-established journal is the official scholarly publication of the Association of Academic Physiatrists (AAP).
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