生命最后几周跌倒的发生率以及跌倒、独立性和死亡质量之间的关系:一项大型前瞻性队列研究的二次分析

Hiroyuki Otani, Shimoinaba Junichi, Kashiwagi Hideyuki, Morita Tatsuya, Maeda Isseki, Yokomichi Naosuke, Hamano Jun, Yamaguchi Takashi, Takashi Yamaguchi, Masanori Mori
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摘要

目的:确定姑息治疗病房(PCU)中跌倒的频率及其严重并发症,并探讨跌倒、独立性和死亡质量之间复杂的相互作用:2017年1月至2018年6月,对日本23个PCU的大型前瞻性队列研究进行了二次分析。姑息治疗专科医生记录了患者是否跌倒、跌倒引起的严重并发症、导致跌倒的活动、独立性(最后几天的工作能力和留置导尿管的使用情况)以及良好死亡量表:在接受评估的 1,633 名患者中,9.2%(95% 置信区间 [95% CI 7.8 至 11])的患者在死亡前 30 天内发生过跌倒。跌倒患者多为男性,入院时东部合作肿瘤学组表现为3级,入院时估计预后较长,住院期间出现谵妄。严重跌倒导致骨折或颅内出血的情况很少见(0.3% [95% CI 0.038 to 0.57])。最常见的跌倒原因是需要上厕所。良好死亡量表和留置导尿管的使用与跌倒无明显关系。结论PCU病房中约有10%的患者会发生跌倒,但严重并发症并不多见。跌倒、独立性和死亡质量之间的关系很复杂;也就是说,如果跌倒是尊重病人独立性的结果,那么跌倒并不一定是坏事。医疗服务提供者需要考虑预防跌倒,同时支持患者自行移动以保持独立性的愿望。
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Prevalence of falls in the last weeks of life and relationship between falls, independence, and quality of dying: A secondary analysis of a large prospective cohort study
Objective: To determine the frequency of falls and their serious complications in palliative care units (PCUs), as well as explore the complex interplay between falls, independence, and quality of dying. Methods: A secondary analysis of a large prospective cohort study of 23 PCUs in Japan was conducted from January 2017 to June 2018. Palliative care specialist physicians recorded whether patients experienced falls, serious complications from falls, activities that led to falls, independence (workability in the last days and use of indwelling urinary catheter), and Good Death Scale. Results: Of the 1,633 patients evaluated, 9.2% (95% Confidence interval [95% CI 7.8 to 11]) experienced falls within 30 days prior to death. The patients who fell were mostly men, had eastern cooperative oncology group performance status 3 on admission, a longer estimated prognosis on admission, and delirium during hospitalization. Serious falls causing fractures or intracranial hemorrhages were rare (0.3% [95% CI 0.038 to 0.57]). The most common reason for falls was the need to use the toilet. The Good Death Scale and indwelling urinary catheter use were not significantly associated with falls. Conclusion: Falls occur in approximately 10% of patients in PCUs, but serious complications are rare. The relationship between falls, independence, and quality of dying is complex; that is, a fall may not be necessarily bad, if it is the result of respect for the patient's independence. Healthcare providers need to consider fall prevention while supporting patients desire to move on their own to maintain independence.
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