比较昂丹司琼和地塞米松对脊髓麻醉患者剖腹产术后颤抖的影响

Mohammad Saleh Sadeghi, Negar Vakili Razlighi, Hadi Vakili Razlighi
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摘要

背景:哆嗦是脊髓麻醉后最常见的问题之一,可引起多种并发症。目前已有多种方法和药物用于预防和治疗术后颤抖。本研究探讨了昂丹司琼和地塞米松对降低脊麻择期剖宫产术后颤抖发生率的预处理效果:本研究评估了78例符合研究条件的择期剖宫产手术患者,并将其随机分为两组:在手术结束前15分钟服用8毫克昂丹司琼和4毫克地塞米松。然后,在手术后的特定时间间隔测量颤抖发生率。统计分析使用 SPSS 软件进行:两组患者在年龄、身高、体重和体重指数方面相似(P 值 > 0.05)。昂丹司琼组在进入恢复期 10、20 和 30 分钟时的颤抖发生率分别为 23.1%、20.5%、12.8% 和 0%,地塞米松组分别为 20.5%、15.4%、5.2% 和 0%。统计分析显示,在 0.05 的显著性水平下,这些差异并不明显。这两种药物对脊髓麻醉下剖宫产术后的颤抖控制效果相同(P 值 > 0.05):结论:地塞米松和昂丹司琼能够控制脊髓麻醉下剖宫产术后的颤抖。
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Comparison of the Effect of Ondansetron and Dexamethasone on Postoperative Shivering After Cesarean Section in Patients Undergoing Spinal Anesthesia
Background: Shivering is one of the most common problems after spinal anesthesia, which can cause many complications. Various methods and drugs have been used to prevent and treat postoperative shivering. In the present study, the pretreatment effect of ondansetron and dexamethasone in reducing the incidence of shivering after elective caesarean section by the spinal method has been investigated. Methods: In this study, 78 patients undergoing elective cesarean surgery who were eligible to enter the study were evaluated and randomly divided into two groups: 8mg of ondansetron and 4mg of dexamethasone 15 minutes before the end of surgery. Then, the incidence of shivering was measured at specific time intervals after surgery. Statistical analysis was done using SPSS software. Results: The two groups were similar in terms of age, height, weight, and BMI (p-value > 0.05). The incidence of shivering at the time of entering the recovery, 10, 20, and 30 minutes in the ondansetron group was 23.1%, 20.5%, 12.8% and 0% and in the dexamethasone, group was 20.5%, 15.4%, 5.2% and 0%, respectively. Statistical analysis showed that these differences are not significant at the significance level of 0.05. These two drugs have the same effectiveness in controlling shivering after cesarean section under spinal anesthesia (p-value > 0.05). Conclusion: Dexamethasone and ondansetron will be able to control shivering after caesarean section with spinal anesthesia.
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