评估肩部手术后在臂丛神经阻滞中使用硬膜外地塞米松复合制剂的镇痛效果

M. Ghasemi, Arman Janparvar, F. Behnaz, F. Taheri
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摘要

研究背景本研究旨在探讨肩部手术后在臂丛神经疤痕间阻滞中使用硬膜外地塞米松复合制剂的镇痛效果。研究方法本研究设计为随机双盲临床试验。符合特定标准的患者被随机分为两组:实验组和对照组各 30 人。两组患者的年龄和性别相匹配。对照组接受利多卡因以及 2 毫升 0.5% 布比卡因(20 毫克)和 2 毫升生理盐水;而实验组则接受利多卡因以及 2 毫升 0.5% 布比卡因和 2 毫升地塞米松。疼痛程度使用视觉模拟量表(VAS)进行评估,数据分析采用协方差分析法。结果结果表明,在术后 12 小时组(P < 0.001)和 24 小时组(P < 0.001),实验组(地塞米松)的疼痛强度明显低于对照组。地塞米松能明显减轻患者的疼痛。结论:总之,对可能接受肩部手术的患者使用地塞米松可使镇痛时间延长至术后24小时。因此,地塞米松可作为一种有效的镇痛药物用于这些患者的疼痛治疗。
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Evaluation of Analgesia Using Perineural Dexamethasone Compound in Interscalene Brachial Plexus Block After Shoulder Surgery
Background: The objective of this study was to examine analgesia when using perineural dexamethasone compound in an interscalene brachial plexus block following shoulder surgery. Methods: This study was designed as a randomized, double-blind clinical trial. Patients meeting the specified criteria were randomly divided into two groups: The experimental group and the control group, each comprising 30 individuals. Age and gender were matched between the groups. The control group received lidocaine along with 2 cc of 0.5% bupivacaine (20 milligrams) and 2 cc of normal saline; however, the experimental group received lidocaine, along with 2 cc of 0.5% bupivacaine and 2 cc of dexamethasone. Pain levels were assessed using the Visual Analog Scale (VAS), and covariance analysis was applied for data analysis. Results: The results demonstrated that pain intensity was notably lower in the experimental (dexamethasone) group than in the control group at both the 12-hour group (P < 0.001) and 24-hour (P < 0.001) postoperative marks. Dexamethasone significantly reduced pain among the patients. Conclusions: In conclusion, administering dexamethasone to potential candidates for shoulder surgery could lead to prolonged analgesia for up to 24 hours after the surgery. Consequently, this medication can serve as an efficacious analgesic option for pain management in these patients.
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