婴幼儿脱水和电解质紊乱口服治疗的最新进展:系统回顾

Sarah Emad Alsayed
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引用次数: 0

摘要

背景:急救人员识别和有效治疗低血容量性休克的能力将决定严重血容量耗竭的患儿能否在急诊室存活下来。尽管对液体和电解质疗法的基本原理已经研究了数十年,但由于没有一种普遍接受的治疗护理方法,因此这一问题仍然难以解决。目的:本系统综述旨在研究儿童和婴儿脱水和电解质紊乱的最新治疗方法。研究方法系统检索了 PubMed、Science Direct 和 Google Scholar 上的相关文献。在整个综合过程中使用了 Rayyan QRCI。结果与解释:本综述共包括 10 项研究,2285 名患者,其中 883 名(38.6%)为男性。根据这项综合研究,家庭治疗和口服体液补充剂在直接的情况下是成功的。其他方法,如口服补液盐加木糖醇和口服补液盐加蜜蜂,在减少呕吐和腹泻频率方面安全有效。稀释苹果汁、补液疗法和首选液体可改善患者的电解质平衡和补液情况。然而,事实证明鞣酸明胶对儿童补液无效,尽管它建议永远不要停止母乳喂养。在口服补液盐无效的情况下,静脉注射甲氧氯普胺和多潘立酮等药物可有效治疗小儿脱水。
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Updates in Oral Management of Dehydration and Electrolyte Disturbance in Infants and Children: A Systematic Review
Background: The ability of the first responder to identify and effectively treat hypovolemic shock will determine whether or not a child with severe volume depletion survives in the emergency room. Although the fundamentals of fluid and electrolyte therapy have been studied for decades, the issue is still difficult to resolve because there is no universally accepted therapeutic care approach. Objectives: This systematic review aims to study the updated management of dehydration and electrolyte disturbance in children and infants. Methods: PubMed, Science Direct, and Google Scholar were systematically searched for relevant literature. Rayyan QRCI was employed throughout this comprehensive process. Results & interpretation: This review included a total of ten studies with 2285 patients, and 883 (38.6%) were males. According to this comprehensive study, home-based therapy and ORS were successful in straightforward instances. Other methods, such as ORS plus Xyloglucan and ORS with honeybee added, were secure and efficient in reducing the frequency of vomiting and diarrhea. The electrolyte balance and rehydration of the patients were improved by diluted apple juice, rehydration treatments, and preferred fluids. However, gelatin tannate proved ineffective for rehydrating the child, although it advised against ever stopping breastfeeding. Drugs like intravenous Metoclopramide and Domperidone demonstrated efficacy for treating pediatric dehydration in the event that ORS failed.
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