血流建模双曲线问题的全局解决方案

IF 2 4区 生物学 Q2 BIOLOGY Biosystems Pub Date : 2024-02-20 DOI:10.1016/j.biosystems.2024.105160
Nie Dayong
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引用次数: 0

摘要

本文旨在研究支配一维血液动力学的双曲方程组及其在分析机械影响下血流的相关性,特别强调改变腿轴角度的影响。根据双曲方程的性质和特点,开发了解决双曲方程的方法和途径。本研究的主要目的是研究静脉压力、脉搏波速度和血管扩张之间的相互作用。研究显示,静脉压力与脉搏波速度之间存在反比关系。静脉压力升高时,脉搏波速度降低,反之亦然。实际测量和建模结果都证实了这种依赖关系。静脉压力介于 10.8 和 13.6 千帕之间,脉搏波速度介于 0.061 和 0.27 千帕之间。真实数据与模型数据的一致性很高。模拟的静脉压和脉搏波速度值接近实际值。然而,必须承认本文的局限性。这些局限性包括采用了一维血流动力学模型,未能考虑循环系统的三维结构。此外,分析仅限于研究腿轴角度的变化。这项研究有助于阐明机械动作与血液动力学参数之间的关系。这些发现可能有助于研究和开发新的方法,用于识别和治疗与心血管系统有关的疾病。
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A global solution to a hyperbolic problem for blood flow modelling

The paper aims to examine the hyperbolic system of equations governing one-dimensional haemodynamics and its relevance in analysing blood flow under mechanical influences, with particular emphasis on the impact of altering the angle of the leg axis. Methods and approaches for solving hyperbolic equations have been developed in light of their properties and characteristics. The primary objective of this study was to investigate the interplay between vein pressure, pulse wave velocity, and vascular distension. The study revealed an inverse relationship between vein pressure and pulse wave velocity. A decrease in pulse wave velocity occurs when vein pressure rises, and vice versa. Both real measurements and modelling results confirmed this dependence. The pressure in the veins is between 10.8 and 13.6 kPa, and the speed of the pulse wave is between 0.061 and 0.27 kPa. The agreement between real and model data was high. The modelled venous pressure and pulse wave velocity values are close to the actual values. However, it is essential to acknowledge the limitations of this paper. These limitations include the utilisation of one-dimensional haemodynamic models, which fail to consider the three-dimensional structure of the circulatory system. Additionally, the analysis is restricted to examining changes solely in the leg axis angle. The research helps to clarify the relationship between mechanical actions and haemodynamic parameters. The findings may help research and develop new methods for identifying and treating conditions associated with the cardiovascular system.

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来源期刊
Biosystems
Biosystems 生物-生物学
CiteScore
3.70
自引率
18.80%
发文量
129
审稿时长
34 days
期刊介绍: BioSystems encourages experimental, computational, and theoretical articles that link biology, evolutionary thinking, and the information processing sciences. The link areas form a circle that encompasses the fundamental nature of biological information processing, computational modeling of complex biological systems, evolutionary models of computation, the application of biological principles to the design of novel computing systems, and the use of biomolecular materials to synthesize artificial systems that capture essential principles of natural biological information processing.
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