为 SBO 设计心电图:用于 CT 肠梗阻检测和定性的神经网络

Paul M Murphy
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摘要

我们开发了一种神经网络,用于检测和描述急性腹痛的常见原因--肠梗阻。在这项回顾性研究中,共纳入了 2022 年 3 月至 6 月期间 165 名肠梗阻患者的 202 张 CT 扫描图像,并将其分为训练数据集和测试数据集。研究人员对多通道神经网络进行了训练,以分割胃肠道,并使用一种新型嵌入方法预测胃肠道的直径和纵向位置("经度")。其性能与使用骰子评分的人工分段以及使用类内相关系数(ICC)的人工直径和经度测量结果进行了比较。计算了直径超过临床梗阻阈值时的 ROC 曲线以及灵敏度和特异性,以及与小肠相对应的经度。在测试数据集中,胃肠道分割的 Dice 得分为 78 ± 8%。测量直径与预测直径之间的 ICC 为 0.72,表明两者之间的一致性适中。测量经度和预测经度之间的 ICC 为 0.85,表明一致性良好。检测扩张肠道的 AUROC 为 0.90,区分近端和远端胃肠道的 AUROC 分别为 0.95 和 0.90。小肠扩张的总体敏感性和特异性分别为 0.83 和 0.90。由于梗阻是根据肠道的直径和经度来诊断的,因此这种神经网络和嵌入可能有助于在 CT 上检测和描述这种重要疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Towards an EKG for SBO: A Neural Network for Detection and Characterization of Bowel Obstruction on CT.

A neural network was developed to detect and characterize bowel obstruction, a common cause of acute abdominal pain. In this retrospective study, 202 CT scans of 165 patients with bowel obstruction from March to June 2022 were included and partitioned into training and test data sets. A multi-channel neural network was trained to segment the gastrointestinal tract, and to predict the diameter and the longitudinal position ("longitude") along the gastrointestinal tract using a novel embedding. Its performance was compared to manual segmentations using the Dice score, and to manual measurements of the diameter and longitude using intraclass correlation coefficients (ICC). ROC curves as well as sensitivity and specificity were calculated for diameters above a clinical threshold for obstruction, and for longitudes corresponding to small bowel. In the test data set, Dice score for segmentation of the gastrointestinal tract was 78 ± 8%. ICC between measured and predicted diameters was 0.72, indicating moderate agreement. ICC between measured and predicted longitude was 0.85, indicating good agreement. AUROC was 0.90 for detection of dilated bowel, and was 0.95 and 0.90 for differentiation of the proximal and distal gastrointestinal tract respectively. Overall sensitivity and specificity for dilated small bowel were 0.83 and 0.90. Since obstruction is diagnosed based on the diameter and longitude of the bowel, this neural network and embedding may enable detection and characterization of this important disease on CT.

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