阿根廷人类孢子丝虫病病例中巴西孢子丝虫的基因分型和克隆起源

IF 1.6 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Medical Mycology Case Reports Pub Date : 2024-02-16 DOI:10.1016/j.mmcr.2024.100633
Norma B. Fernandez , Bram Spruijtenburg , Iris N. Tiraboschi , Jacques F. Meis , Ana Lugo , María Cecilia López Joffre , Eelco F.J. Meijer
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引用次数: 0

摘要

巴西孢子丝菌(Sporothrix brasiliensis)被认为是一种毒性很强的新病原体,主要通过受感染的猫进行人畜共患病传播,导致人类患上孢子丝菌病。这种源于巴西的人畜共患传染病在过去几十年中不断蔓延,在拉丁美洲形成了高流行区。我们在阿根廷布宜诺斯艾利斯发现了两例由巴西猫孢子丝菌引起的人类孢子丝菌病病例,患者在接触病猫后对不同的治疗方法临床反应良好。通过短串联重复序列(STR)基因分型,这两例 S. brasiliensis 似乎是从巴西引入的,很可能来自同一来源。
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Genotyping and clonal origin of Sporothrix brasiliensis in human sporotrichosis cases in Argentina

Sporothrix brasiliensis is considered a highly virulent emerging pathogen that causes sporotrichosis in humans, mainly after zoonotic transmission from infected cats. The epidemic of this zoonosis that originated from Brazil has spread in the last decades, generating hyperendemic regions in Latin America. We present two cases of human sporotrichosis causes by S. brasiliensis in Buenos Aires, Argentina, with good clinical response to differing treatments after contact with sick cats. Using Short tandem repeat (STR) genotyping, the two S. brasiliensis cases appear to be introduced from Brazil and likely originate from the same source.

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来源期刊
Medical Mycology Case Reports
Medical Mycology Case Reports MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
4.00
自引率
0.00%
发文量
48
审稿时长
47 days
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