Berdazimer 外用凝胶，10.3%：首次批准。

IF 13 1区医学 Q1 PHARMACOLOGY & PHARMACY Drugs Pub Date : 2024-03-01 DOI:10.1007/s40265-024-02012-9

Susan J Keam

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引用次数: 0

摘要

Berdazimer 10.3% 外用凝胶（ZELSUVMI™）是一种一氧化氮（NO）释放型外用凝胶，由 Novan 公司（Ligand 制药公司旗下公司）开发，用于治疗软疣 (MC)。诺万公司利用其基于一氧化氮的专有技术平台 (NITRICIL™)，将气态一氧化氮储存在大型聚合物上，开发出了浓度为 10.3% 的 berdazimer 外用凝胶。2024 年 1 月，10.3% berdazimer 外用凝胶在美国获准用于 1 岁及以上成人和儿童患者 MC 的局部治疗。本文总结了 Berdazimer 外用凝胶（10.3%）开发过程中的里程碑事件，这些事件促成了 Berdazimer 外用凝胶（10.3%）首次获准用于治疗 MC。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Berdazimer Topical Gel, 10.3%: First Approval.

Berdazimer topical gel, 10.3% (ZELSUVMI™) is a nitric oxide (NO) releasing topical gel developed by Novan Inc. (a Ligand Pharmaceuticals company) for the treatment of molluscum contagiosum (MC). Novan has used their proprietary NO-based technology platform (NITRICIL™), which stores gaseous NO species on large polymers, in the development of berdazimer topical gel, 10.3%. In January 2024, berdazimer topical gel, 10.3% was approved for the topical treatment of MC in adult and paediatric patients 1 year of age and older in the USA. This article summarizes the milestones in the development of berdazimer topical gel, 10.3% leading to this first approval for the treatment of MC.

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来源期刊

Drugs 医学-毒理学

CiteScore

22.70

自引率

0.90%

发文量

134

审稿时长

3-8 weeks

期刊介绍： Drugs is a journal that aims to enhance pharmacotherapy by publishing review and original research articles on key aspects of clinical pharmacology and therapeutics. The journal includes: Leading/current opinion articles providing an overview of contentious or emerging issues. Definitive reviews of drugs and drug classes, and their place in disease management. Therapy in Practice articles including recommendations for specific clinical situations. High-quality, well designed, original clinical research. Adis Drug Evaluations reviewing the properties and place in therapy of both newer and established drugs. AdisInsight Reports summarising development at first global approval. Moreover, the journal offers additional digital features such as animated abstracts, video abstracts, instructional videos, and podcasts to increase visibility and educational value. Plain language summaries accompany articles to assist readers with some knowledge of the field in understanding important medical advances.