作为新型抗肥胖药物的天然产品:基于脂肪组织的机理。

IF 2.4 Q3 ENDOCRINOLOGY & METABOLISM Current diabetes reviews Pub Date : 2024-02-23 DOI:10.2174/0115733998278959240216044936
Lei Cao, Chunwei Wu, Miao Liu, Wenlong Zhang, Hailong Chen, Ruolin Wang, Ze He
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引用次数: 0

摘要

肥胖症是目前全球公共卫生的一个严重问题,对人类的生活和福祉产生了深远的影响。尽管针对肥胖症的药物干预措施层出不穷,但由于在药物干预过程中出现了许多不良反应,阻碍了它们在临床上的广泛应用。传统中药、水果和蔬菜中的天然化合物或提取物具有多种特性,如调节代谢、诱导生热、改变食欲、抑制脂肪酶活性和脂肪合成等,因此被定位为潜在的抗肥胖候选药物。通过脂肪组织褐变促进生热、减少脂肪组织生成和异位沉积以及调节脂肪因子,已成为治疗肥胖症的主要重点。这一转变凸显了脂肪组织作为肥胖症治疗关键靶点的重要作用。本研究深入探讨了基于脂肪组织的各种方法,概述了从药用植物和水果中提取的生物活性成分通过调节脂肪组织治疗肥胖症的功效。我们从动物实验和临床应用中汲取了启示,并讨论了这些作用的潜在机制。总之,我们已经确定,天然化合物是治疗肥胖症的重要候选物质,而脂肪组织是治疗过程中的关键目标。我们希望我们的研究能为未来药物和膳食补充剂的开发提供新的视角,并为该领域的临床试验提供创新方向。
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WITHDRAWN: The Natural Products as Novel Anti-Obesity Agents: Mechanisms Based on Adipose Tissue

The article has been withdrawn at the request of the authors of the journal Current Diabetes Reviews.

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php

Bentham science disclaimer: It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal right to take appropriate action against the authors if plagiarism or fabricated information is discovered. By submitting a manuscript the authors agree that the copyright of their article is transferred to the publishers if and when the article is accepted for publication.

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来源期刊
Current diabetes reviews
Current diabetes reviews ENDOCRINOLOGY & METABOLISM-
CiteScore
6.30
自引率
0.00%
发文量
158
期刊介绍: Current Diabetes Reviews publishes frontier reviews on all the latest advances on diabetes and its related areas e.g. pharmacology, pathogenesis, complications, epidemiology, clinical care, and therapy. The journal"s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians who are involved in the field of diabetes.
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