利用可部分溶解的天线连续探测漏入人体的液体

IF 3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology Pub Date : 2024-02-19 DOI:10.1109/JERM.2024.3363509
Federica Naccarata;Marco Di Cristofano;Gaetano Marrocco
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引用次数: 0

摘要

人体内部液体渗漏可能是由潜在的疾病引起的。渗漏也可能与用于治疗腹部动脉瘤的植入支架移植物有关。事实上,血液可能会通过支架渗漏到动脉瘤囊中,由于内压增加而有破裂的危险。由于无法频繁进行标准筛查,本文提出了利用部分包裹工程材料的植入式天线和超高频射频识别(UHF RFID)频段的自动调谐集成电路,对渗漏到人体区域的液体进行无线监测。液体的存在会通过涂层的水解以可控的方式改变天线的阻抗。即使天线被植入 6 厘米处,也能通过外部读取器的射频询问获得这种变化的指示。模拟实验表明,该传感器能够分辨生物可吸收涂层的降解情况。该传感器对高达 3.5 mm$^{3}$ 的溶解涂层反应灵敏,灵敏度超过 10 个单位$/$mm$^{3}$。只要涂层的尺寸设计得当,传感器就能在与流体发生不可预测的相互作用时保持稳定的响应。
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Continuous Detection of Fluid Leaks Into the Body by Means of Partially Dissolvable Antennas
Internal fluid leaks in the human body can be caused by underlying medical disorders. Leakage may also be relevant to implanted stent grafts for the treatment of abdominal aneurysms. Indeed, blood may leak through the stent into the aneurysm sac with the risk of rupture due to increased internal pressure. As standard screenings cannot be performed frequently enough, this paper proposes wireless monitoring of fluid leaks into human body regions exploiting an implanted antenna partially coated by an engineered material and an auto-tuning IC in the UHF RFID band. The presence of fluid modifies the antenna impedance in a controlled way by the hydrolysis of the coating. An indication of this change can be obtained through radiofrequency interrogation from an external reader even when the antenna is implanted at 6 cm. Simulations and tests with a mock-up demonstrated the ability to distinguish the degradation of the bioresorbable coating. The sensor is responsive to up to 3.5 mm $^{3}$ of dissolved coating, with a sensitivity of more 10 units $/$ mm $^{3}$ . Provided that the size of the coating has been properly engineered, the response of the sensor is robust w.r.t. the unpredictable interaction with the fluid.
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CiteScore
5.80
自引率
9.40%
发文量
58
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Front Cover Table of Contents IEEE Journal of Electromagnetics, RF, and Microwaves in Medicine and Biology About this Journal IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology Publication Information Models of Melanoma Growth for Assessment of Microwave-Based Diagnostic Tools
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