Green Synthesis of Silica Nanoparticles/Nanocomposites for Biomedical Applications: A Narraitive Review

Nanomedicine showed the unique benefits in clinical outcomes in comparison with traditional and conventional drugs in the treatment of cancer. In the future, nanomedicine therapy seems to pave the way for new treatments in cancer. In this regard, silica nanoparticles are used in various fields of technology, biomedicine and biosensing techniques due to their unique properties such as stability, biocompatibility, high surface area, significant reactivity and functionalizability. Although there are various physical and chemical methods for synthesizing silica nanoparticles, its synthesis by green method has other significant features such as being environmentally friendly, cost-effective, saving time and eliminating toxic compounds and harmful by-products that increase their application in the field of biomedicine. In the method of green synthesis of silica nanoparticles, various sources such as plants, fungi, bacteria, yeast, actinomycetes, etc. are used. In this narraitive review, various biomedical applications of green synthesized silica nanoparticles are discussed along with their examples.