癌症中的代谢性细胞死亡：铁蜕变、杯蜕变、二硫化碳蜕变及其他。

IF 13.6 1区生物学 Q1 CELL BIOLOGY Protein & Cell Pub Date : 2024-09-01 DOI:10.1093/procel/pwae003

Chao Mao, Min Wang, Li Zhuang, Boyi Gan

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引用次数: 0

摘要

细胞死亡抵抗是癌症的一个特征。最近的研究发现，代谢性细胞死亡是由细胞代谢失衡导致的独特形式的调节性细胞死亡。这篇综述讨论了代谢性细胞死亡的机制--铁凋亡、杯凋亡、二硫化碳凋亡、溶菌酶死和碱凋亡，并探讨了它们在癌症治疗中的潜力。我们的综述强调了代谢性细胞死亡途径的复杂性，并为癌症治疗的创新疗法提供了见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Metabolic cell death in cancer: ferroptosis, cuproptosis, disulfidptosis, and beyond.

Cell death resistance represents a hallmark of cancer. Recent studies have identified metabolic cell death as unique forms of regulated cell death resulting from an imbalance in the cellular metabolism. This review discusses the mechanisms of metabolic cell death-ferroptosis, cuproptosis, disulfidptosis, lysozincrosis, and alkaliptosis-and explores their potential in cancer therapy. Our review underscores the complexity of the metabolic cell death pathways and offers insights into innovative therapeutic avenues for cancer treatment.

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来源期刊

Protein & Cell CELL BIOLOGY-

CiteScore

24.00

自引率

0.90%

发文量

1029

审稿时长

6-12 weeks

期刊介绍： Protein & Cell is a monthly, peer-reviewed, open-access journal focusing on multidisciplinary aspects of biology and biomedicine, with a primary emphasis on protein and cell research. It publishes original research articles, reviews, and commentaries across various fields including biochemistry, biophysics, cell biology, genetics, immunology, microbiology, molecular biology, neuroscience, oncology, protein science, structural biology, and translational medicine. The journal also features content on research policies, funding trends in China, and serves as a platform for academic exchange among life science researchers.