作为隐形眼镜设计关键材料的乙烯基聚合物:进展回顾与未来方向

Starch Pub Date : 2024-03-02 DOI:10.1002/star.202300213
Lina M. Shaker, Ahmed Al‐Amiery, Wan Nor Roslam Wan Isahak, Waleed Khalid Al‐Azzawi
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摘要

乙烯基聚合物是当代隐形眼镜设计的关键,它具有独特的属性,对视力矫正具有重要意义。这篇全面的综述介绍了以乙烯基聚合物为基础的隐形眼镜的发展轨迹和未来发展方向。导言强调了隐形眼镜在视力矫正中的重要作用,并将乙烯基聚合物定位为具有特殊属性的理想材料。分析深入探讨了材料的具体特性--高透氧性、光学清晰度、表面润湿性和机械强度,强调了它们对角膜健康、舒适度和耐用性的影响。制造技术的多样性,包括旋铸、成型工艺、聚合和表面改性,强调了它们在制作高质量镜片方面的可行性。通过对临床应用的研究,包括日抛型、超长戴型、硅水凝胶型和特种镜片,以及生物相容性评估和用户反馈,让我们对乙烯基聚合物镜片的功效有了细致入微的了解。文章坦率地探讨了面临的挑战--脱水、沉积物、机械稳定性和耐用性--以及监管方面的考虑。未来前景涉及新型配方、智能材料、生物启发设计和无创技术,以提高舒适度和性能。总之,本综述总结了在隐形眼镜设计方面取得的进展、面临的挑战,并为乙烯基聚合物材料的发展指明了方向,展望了以增强视力矫正技术为标志的未来。
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Vinyl Polymers as Key Materials in Contact Lens Design: A Review of Progress and Future Directions
Vinyl polymers, crucial in contemporary contact lens design, present unique attributes with promising implications for vision correction. This comprehensive review navigates the trajectory and future trajectories of vinyl polymer‐based contact lenses. The introduction underscores the vital role of contact lenses in vision correction and positions vinyl polymers as ideal materials due to their exceptional properties. Delving into material specifics—high oxygen permeability, optical clarity, surface wettability, and mechanical strength—the analysis emphasizes their influence on corneal health, comfort, and durability. The versatility of manufacturing techniques, encompassing spin casting, molding processes, polymerization, and surface modification, underscores their feasibility in crafting high‐quality lenses. Examining clinical applications, encompassing daily disposables, extended wear, silicone hydrogel, and specialty lenses, alongside biocompatibility assessments and user feedback, provides a nuanced understanding of vinyl polymer‐based lens effectiveness. The article candidly addresses challenges—dehydration, deposits, mechanical stability, and durability—alongside regulatory considerations. Future prospects involve novel formulations, smart materials, bioinspired designs, and noninvasive technologies to amplify comfort and performance. In conclusion, this review distills progress, acknowledges challenges, and charts a sanguine course for vinyl polymer materials in advancing contact lens design, envisioning a future marked by enhanced vision correction technologies.
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