一名自闭症和强迫症患者因安非他明引起的秽语和秽语障碍

Q4 Medicine Psiquiatria Biologica Pub Date : 2024-01-01 DOI:10.1016/j.psiq.2024.100444
Belén Sánchez Martín-Moreno, José Ángel Gila Azañedo
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引用次数: 0

摘要

本病例中的患者是一名 41 岁的男性,自 26 岁起就住进了住院和康复部,诊断为自闭症谱系障碍和强迫症,并接受了氟伏沙明、丙戊酸钠、托吡酯、利培酮和氯硝西泮的治疗。经过一段时间的稳定后,出现了与重度抑郁发作相一致的症状,这时就需要使用安非他酮进行治疗,以缓解冷漠和精神运动迟缓的症状。两周后,他的病情迅速恢复,但开始出现以前从未出现过的肢体瘫痪和肢体抽搐。停用安非他酮后,桡神经症状在两周内消失,但他仍有一些这些行为,因此医生给他开了醋酸环丙孕酮来控制这些症状,一周后症状有所改善。停用安非他明三个月后,他达到了健康状态,不再出现任何性行为改变、秽语或秽语障碍。文献证实了其他一些因抑郁而接受抗抑郁药治疗的患者出现抽搐症状以及与强迫症并发的病例,但几乎没有一例因使用安非他酮而出现抽搐症状,也没有一例因使用安非他酮而出现秽语和秽语综合症。
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Coprolalia y copropraxia inducida por bupropión en un paciente autista y con trastorno obsesivo compulsivo

The case is presented of a 41-year-old male, admitted since age 26 to the Residential and Rehabilitation Unit with the diagnoses of autism spectrum disorder and obsessive-compulsive disorder, and under treatment with fluvoxamine, valproic, topiramate, risperidone and clonazepam. After a period of stability, a picture compatible with a major depressive episode appear, which is treated with bupropion, in order to affect the symptoms of apathy and psychomotor slowness. There is a rapid recovery in two weeks, but he begins to present copropraxia and coprolalia, which he had never presented before. Bupropion is withdrawn and coprolalia disappears in two weeks, but he maintained some of these behaviors, so cyproterone acetate is prescribed to control them, with improvement in one week. Three months after withdrawal of bupropion, he reaches euthymia and no longer presented any sexual behavioral alteration, coprolalia or copropraxia. The literature confirms other cases of appearance of tics in patients treated with antidepressants for a depressive picture and comorbidity with obsessive-compulsive disorder, but almost none by the use of bupropion or with coprolalia and copropraxia.

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来源期刊
Psiquiatria Biologica
Psiquiatria Biologica Medicine-Psychiatry and Mental Health
CiteScore
0.40
自引率
0.00%
发文量
13
期刊介绍: Es la Publicación Oficial de la Sociedad Española de Psiquiatría Biológica. Los recientes avances en el conocimiento de la bioquímica y de la fisiología cerebrales y el progreso en general en el campo de las neurociencias han abierto el camino al desarrollo de la psiquiatría biológica, fundada sobre bases anatomofisiológicas, más sólidas y científicas que la psiquiatría tradicional.
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