Muhammad Rizwan, Ke Cheng, Yang Gang, Yuntao Hou, Chunfang Wang
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Ongoing clinical trials are actively investigating their potential therapeutic advantages. Beyond the immediate context of the pandemic, these micronutrients offer valuable tools for enhancing immunity and overall well-being, especially in the face of future viral threats. This analysis emphasizes the enduring significance of VD and Zn as both treatment and preventive measures against potential viral challenges beyond the current health crisis. The overview delves into the immunomodulatory potential of VD and Zn in combating viral infections, with particular attention to their effects on animals. It provides a comprehensive summary of current research findings regarding their individual and synergistic impacts on immune function, underlining their potential in treating and preventing viral infections. Overall, this overview underscores the need for further research to understand how VD and Zn can modulate the immune response in combatting viral diseases in animals.</p>","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":"1-17"},"PeriodicalIF":3.4000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Immunomodulatory Effects of Vitamin D and Zinc on Viral Infection.\",\"authors\":\"Muhammad Rizwan, Ke Cheng, Yang Gang, Yuntao Hou, Chunfang Wang\",\"doi\":\"10.1007/s12011-024-04139-y\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Several nutrients are crucial in enhancing the immune system and preserving the structural integrity of bodily tissue barriers. Vitamin D (VD) and zinc (Zn) have received considerable interest due to their immunomodulatory properties and ability to enhance the body's immune defenses. 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引用次数: 0
摘要
有几种营养素对增强免疫系统和保持身体组织屏障结构的完整性至关重要。维生素 D(VD)和锌(Zn)因其免疫调节特性和增强机体免疫防御能力而受到广泛关注。由于维生素 D 和锌具有抗病毒、抗炎、抗氧化和免疫调节的特性,这两种营养素对先天性免疫和适应性免疫至关重要。正如在 COVID-19 中观察到的那样,缺乏这些微量营养素会损害免疫反应,增加对病毒感染和严重疾病的易感性。确保摄入充足的维生素 D 和锌是强化免疫系统的有效策略。目前正在进行的临床试验正在积极研究它们的潜在治疗优势。除了大流行病的直接影响之外,这些微量营养素还为增强免疫力和整体健康提供了宝贵的工具,尤其是在面对未来的病毒威胁时。本分析报告强调了 VD 和锌作为治疗和预防措施,在应对当前健康危机之外的潜在病毒挑战方面所具有的持久意义。综述深入探讨了 VD 和锌在抗击病毒感染方面的免疫调节潜力,并特别关注了它们对动物的影响。综述全面总结了目前有关这两种物质对免疫功能的单独和协同影响的研究成果,强调了它们在治疗和预防病毒感染方面的潜力。总之,本综述强调了进一步研究的必要性,以了解 VD 和锌如何调节免疫反应,从而防治动物的病毒性疾病。
Immunomodulatory Effects of Vitamin D and Zinc on Viral Infection.
Several nutrients are crucial in enhancing the immune system and preserving the structural integrity of bodily tissue barriers. Vitamin D (VD) and zinc (Zn) have received considerable interest due to their immunomodulatory properties and ability to enhance the body's immune defenses. Due to their antiviral, anti-inflammatory, antioxidative, and immunomodulatory properties, the two nutritional powerhouses VD and Zn are crucial for innate and adaptive immunity. As observed with COVID-19, deficiencies in these micronutrients impair immune responses, increasing susceptibility to viral infections and severe disease. Ensuring an adequate intake of VD and Zn emerges as a promising strategy for fortifying the immune system. Ongoing clinical trials are actively investigating their potential therapeutic advantages. Beyond the immediate context of the pandemic, these micronutrients offer valuable tools for enhancing immunity and overall well-being, especially in the face of future viral threats. This analysis emphasizes the enduring significance of VD and Zn as both treatment and preventive measures against potential viral challenges beyond the current health crisis. The overview delves into the immunomodulatory potential of VD and Zn in combating viral infections, with particular attention to their effects on animals. It provides a comprehensive summary of current research findings regarding their individual and synergistic impacts on immune function, underlining their potential in treating and preventing viral infections. Overall, this overview underscores the need for further research to understand how VD and Zn can modulate the immune response in combatting viral diseases in animals.
期刊介绍:
Biological Trace Element Research provides a much-needed central forum for the emergent, interdisciplinary field of research on the biological, environmental, and biomedical roles of trace elements. Rather than confine itself to biochemistry, the journal emphasizes the integrative aspects of trace metal research in all appropriate fields, publishing human and animal nutritional studies devoted to the fundamental chemistry and biochemistry at issue as well as to the elucidation of the relevant aspects of preventive medicine, epidemiology, clinical chemistry, agriculture, endocrinology, animal science, pharmacology, microbiology, toxicology, virology, marine biology, sensory physiology, developmental biology, and related fields.