新发麻风腮病毒感染概述,重点关注神经系统表现。

IF 9 2区 医学 Q1 VIROLOGY Reviews in Medical Virology Pub Date : 2024-03-01 DOI:10.1002/rmv.2527
Mohammed Alissa, Abdullah Alghamdi, Suad A Alghamdi
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引用次数: 0

摘要

麻腮风是由麻腮风病毒引起的一种重新出现的人畜共患疾病,因其可能出现严重的临床表现而日益受到关注。尽管痘疹的皮肤和全身表现已得到充分证实,但其神经系统并发症近来也成为一个值得关注的领域。本综述简要概述了水痘感染的神经系统方面,重点介绍了在了解和处理这些并发症方面的主要发现和挑战。麻风病人的神经系统表现从头痛和头晕等轻微症状到脑炎和癫痫发作等更严重的病症不等。神经系统受累的发病机制尚未完全阐明,但据认为涉及病毒向中枢神经系统的传播。这种传播可能通过血液或神经元途径发生,从而导致临床表现多种多样。早期识别和诊断水痘的神经系统并发症对于实施适当的治疗干预和改善患者预后至关重要。
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Overview of reemerging mpox infection with a focus on neurological manifestations.

Mpox, a reemerging zoonotic disease caused by the mpox virus, has garnered increasing attention due to its potential for severe clinical manifestations. While the cutaneous and systemic presentations of mpox have been well-documented, its neurological complications have recently emerged as an area of concern. This review provides a brief overview of the neurological aspects of mpox infection, highlighting the key findings and challenges in understanding and managing these complications. Neurological manifestations in mpox patients range from mild symptoms such as headaches and dizziness to more severe conditions, including encephalitis and seizures. The pathogenesis of neurological involvement is not yet fully elucidated but is thought to involve viral dissemination to the central nervous system. This dissemination may occur through haematogenous or neuronal routes, contributing to the diverse clinical spectrum observed. Early recognition and diagnosis of neurological complications in mpox are crucial for implementing appropriate therapeutic interventions and improving patient outcomes.

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来源期刊
Reviews in Medical Virology
Reviews in Medical Virology 医学-病毒学
CiteScore
21.40
自引率
0.90%
发文量
88
期刊介绍: Reviews in Medical Virology aims to provide articles reviewing conceptual or technological advances in diverse areas of virology. The journal covers topics such as molecular biology, cell biology, replication, pathogenesis, immunology, immunization, epidemiology, diagnosis, treatment of viruses of medical importance, and COVID-19 research. The journal has an Impact Factor of 6.989 for the year 2020. The readership of the journal includes clinicians, virologists, medical microbiologists, molecular biologists, infectious disease specialists, and immunologists. Reviews in Medical Virology is indexed and abstracted in databases such as CABI, Abstracts in Anthropology, ProQuest, Embase, MEDLINE/PubMed, ProQuest Central K-494, SCOPUS, and Web of Science et,al.
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