评估树脂浸润对初期龋病发展的抑制作用：使用显微计算机断层扫描分析进行体外研究

IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Saudi Dental Journal Pub Date : 2024-05-01 DOI:10.1016/j.sdentj.2024.03.003

Vongnart Predapramote, Yanee Tantilertanant, Sirivimol Srisawasdi

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引用次数: 0

摘要

材料和方法从人类永久性前臼齿的每个颊面制备两块釉板，共 56 块。诱导人工白斑损伤。其中一个样本用树脂浸润处理，另一个样本作为未处理对照。使用微型计算机断层扫描评估每个标本的病变深度和矿物质密度。随后，对所有试样进行 10,000 次热循环和 pH 循环，持续 10 天，然后使用显微 CT 重新评估。采用配对样本 t 检验法检验和比较每组中老化程序前后的病变深度和矿物质密度。结果老化后，对照组和树脂浸润组的病变深度和矿物质含量都有明显的增加。对照组的平均病变深度为 132.88 ± 4.18 µm，树脂浸润组为 52.31 ± 4.16 µm。对照组和树脂浸润组的矿物质密度损失百分比分别为 16.1 ± 0.64 % 和 8.83 ± 0.30 %。与对照组相比，树脂浸润组的平均病变深度进展和矿物质损失百分比变化都明显较低。临床意义树脂浸润是一种很有前景的方法，可以抑制与龋齿初期有关的白斑病变的进展。

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Evaluation of resin infiltration for inhibiting initial caries progression: An in vitro study using Micro-Computed Tomographic analysis

Objective

To evaluate the changes in lesion depth and mineral density of resin infiltration-treated white spot lesions against a simulated oral environment using thermal and acidic challenges in vitro.

Materials and methods

Two enamel slabs were prepared from each buccal surface of permanent human premolars, for a total of 56 slabs. Artificial white spot lesions were induced. One specimen was treated with resin infiltration, while the other was used as an untreated control. A micro-CT was used to assess the lesion depth and mineral density of each specimen. Subsequently, all specimens were subjected to 10,000 cycles of thermocycling and pH cycling for 10 days before being re-evaluated using the micro-CT. Lesion depth and mineral density were examined and compared between before and after aging procedures within each group by the paired sample t-test. The independent samples t-test was utilized to compare lesion depth progression and percentage change of mineral density between groups.

Results

After aging, there was both a significant lesion depth progression and a mineral loss in the control and resin infiltration groups. Mean lesion depth progression was 132.88 ± 4.18 µm for the control group and 52.31 ± 4.16 µm for resin infiltration group. Percentage mineral density loss as a percentage for the control and resin infiltration groups were 16.1 ± 0.64 % and 8.83 ± 0.30 %, respectively. The resin infiltration group demonstrated a significantly lower mean lesion depth progression and percentage changes in mineral loss compared to the control group.

Conclusions

The lesion depth and mineral density changes in the resin infiltrated-treated group were lower than untreated white spot lesions after aging procedures using thermal and acidic challenges.

Clinical significance

Resin infiltration is a promising approach to inhibit the progression of white spot lesions related to the initial stage of dental caries.

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来源期刊

Saudi Dental Journal DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.60

自引率

0.00%

发文量

审稿时长

22 weeks

期刊介绍： Saudi Dental Journal is an English language, peer-reviewed scholarly publication in the area of dentistry. Saudi Dental Journal publishes original research and reviews on, but not limited to: • dental disease • clinical trials • dental equipment • new and experimental techniques • epidemiology and oral health • restorative dentistry • periodontology • endodontology • prosthodontics • paediatric dentistry • orthodontics and dental education Saudi Dental Journal is the official publication of the Saudi Dental Society and is published by King Saud University in collaboration with Elsevier and is edited by an international group of eminent researchers.