Wen-Chao Gao, Wei Li, Juan Zhang, Hong-Hong Chang, Rong Zhou
{"title":"通过光氧化催化与二硫代羧酸进行温和绿色的硫代酰化反应","authors":"Wen-Chao Gao, Wei Li, Juan Zhang, Hong-Hong Chang, Rong Zhou","doi":"10.1016/j.gresc.2024.02.008","DOIUrl":null,"url":null,"abstract":"<div><div>A photocatalysis process-enabled thioacylation of amines has been developed with eco-friendly feedstock potassium dithiocarboxylates as green thioacyl sources and water as the reaction solvent. The key to the success of this transformation is the light-induced generation of active dithioacyl disulfides as thioacyl donors. This green methodology has been successfully employed for the late-stage thioacylation of various amino compounds including drugs, hormones, amino acids and peptides under mild conditions.</div></div>","PeriodicalId":12794,"journal":{"name":"Green Synthesis and Catalysis","volume":"7 1","pages":"Pages 69-74"},"PeriodicalIF":0.0000,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Mild and green thioacylation with dithiocarboxylates via photoredox catalysis\",\"authors\":\"Wen-Chao Gao, Wei Li, Juan Zhang, Hong-Hong Chang, Rong Zhou\",\"doi\":\"10.1016/j.gresc.2024.02.008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>A photocatalysis process-enabled thioacylation of amines has been developed with eco-friendly feedstock potassium dithiocarboxylates as green thioacyl sources and water as the reaction solvent. The key to the success of this transformation is the light-induced generation of active dithioacyl disulfides as thioacyl donors. This green methodology has been successfully employed for the late-stage thioacylation of various amino compounds including drugs, hormones, amino acids and peptides under mild conditions.</div></div>\",\"PeriodicalId\":12794,\"journal\":{\"name\":\"Green Synthesis and Catalysis\",\"volume\":\"7 1\",\"pages\":\"Pages 69-74\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2026-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Green Synthesis and Catalysis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2666554924000280\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/3/7 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Green Synthesis and Catalysis","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666554924000280","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/3/7 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
Mild and green thioacylation with dithiocarboxylates via photoredox catalysis
A photocatalysis process-enabled thioacylation of amines has been developed with eco-friendly feedstock potassium dithiocarboxylates as green thioacyl sources and water as the reaction solvent. The key to the success of this transformation is the light-induced generation of active dithioacyl disulfides as thioacyl donors. This green methodology has been successfully employed for the late-stage thioacylation of various amino compounds including drugs, hormones, amino acids and peptides under mild conditions.
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