苏巴斯-穆克吉博士作品存档:印度试管婴儿的设计师

IF 0.1 Q4 HISTORY & PHILOSOPHY OF SCIENCE INDIAN JOURNAL OF HISTORY OF SCIENCE Pub Date : 2024-03-14 DOI:10.1007/s43539-024-00117-4
Srabani Mukherjee, Rajvi Mehta
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引用次数: 0

摘要

印度的第一个试验婴儿--卡努普里亚,又名杜尔加,于 1978 年 10 月 3 日出生,比英国的路易丝-布朗出生仅晚 67 天。她是印度加尔各答的生殖生物学家苏巴斯-穆克吉博士(Dr. Subhas Mukherjee)的心血结晶。这个想法在当时是非常超前的。因此,它遭到了严厉的批评和拒绝。苏巴斯博士面临着严重的羞辱、不断的否定和多次调职。这导致他于 1981 年 6 月 19 日不幸去世。1997 年,孟买生殖研究所(现为 ICMR-NIRRCH)前所长 T. C. Anand Kumar 博士,即 1986 年促成印度第一个 "有科学依据 "的试管婴儿 "Harsha "诞生的团队负责人,对穆克吉博士的日记、论文和有关其技术的手写笔记进行了评估。2002 年,在他去世 21 年后,ICMR 首次认可了他的工作。穆克吉博士将体外受精和冷冻保存人类胚胎相结合的方法是目前首选的医学辅助生殖技术。2010 年,爱德华兹博士因创造试管婴儿而获得诺贝尔奖。虽然苏巴斯-穆克吉博士是第一个发现这一过程的亚洲人,也是第一个发现冷冻胚胎活产的人,但他生前从未获得过认可。直到现在,他也没有获得过任何如此重大的荣誉。由于当局的限制和禁止,苏巴斯博士的许多研究成果仍未发表。我们认为,有必要保存和记录穆克吉博士的作品,使其在印度家喻户晓。为此,有必要对所有现有资料进行细致、公正和透彻的分析。本项目正是为此而开展的。
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Archiving the work of Dr. Subhas Mukherjee: The architect of India’s test tube baby

India’s first test baby-Kanupriya, also known as Durga, was born on 3 October 1978, just 67 days after the birth of Louise Brown in England. She was the brainchild of Dr. Subhas Mukherjee, a reproductive biologist from Kolkata, India. This idea was way ahead of its time. Thus, it met with harsh criticism and rejection. Dr. Subhas faced severe humiliation, constant repudiation, and multiple transfers. This led to his tragic death on 19 June 1981. In 1997, Dr. T. C. Anand Kumar, former director of the Institute of Research in Reproduction (now ICMR-NIRRCH), Mumbai, who had headed the team that led to the birth of India’s first ‘scientifically documented’ test-tube baby ‘Harsha’ in 1986, assessed Dr. Mukherjee’s diaries, papers, and handwritten notes on his technique and after that credited Dr. Mukherjee by extensively writing about his pioneering feat. In 2002, after 21 years of his death, ICMR recognized his work for the first time. Dr. Mukherjee’s method of combining in vitro fertilization and cryopreservation of human embryos is the currently preferred technique of medically assisted reproduction. Dr. Edwards was awarded the Nobel Prize for creating a test tube baby in 2010. Though Dr. Subhas Mukherjee was the first Asian to discover such a process and the first to discover live birth from frozen embryos, he never got recognition during his lifetime. Till now, he has not received any honor of such magnitude. Much of Dr. Subhas’s work remains unpublished because of restrictions and prohibitions by the authorities. We believe, there is a need to preserve and document Dr. Mukherjee’s work to make it a familiar name in India. For this purpose, meticulous, unbiased, and thorough analysis of all the available material was necessary. This project was undertaken with this intention.

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INDIAN JOURNAL OF HISTORY OF SCIENCE
INDIAN JOURNAL OF HISTORY OF SCIENCE HISTORY & PHILOSOPHY OF SCIENCE-
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