衰老过程受能量平衡的影响:关注营养和体育活动对端粒长度的影响。

IF 4.6 3区 医学 Q1 NUTRITION & DIETETICS Current Nutrition Reports Pub Date : 2024-06-01 Epub Date: 2024-03-18 DOI:10.1007/s13668-024-00529-9
Satı Gürel, Elif Nisa Pak, Nilüfer Acar Tek
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引用次数: 0

摘要

审查目的:全球 60 岁及以上人口的数量和比例都在增加。老年人口的增加对社会和经济产生了重要影响。端粒长度是健康老龄化的重要标志。在此,我们通过确定体力活动、营养素、膳食模式和食物对健康老龄化和端粒长度的影响以及相关研究,回顾了端粒长度和能量平衡之间的相关性:最新发现:有证据强调端粒长度和完整性对健康老龄化的重要性。证据还强调了体育锻炼和健康饮食等潜在干预措施对改善这一过程的重要性。我们认为,通过有规律的体育锻炼和健康饮食来确保能量平衡,可以通过保护端粒长度来促进衰老过程。此外,不同的研究方法、短时间和不一致的持续时间、不同的运动类型、不同的饮食模式和非标准食品也导致了相互矛盾的结果。还需要更多的研究来阐明分子机制。
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Aging Processes Are Affected by Energy Balance: Focused on the Effects of Nutrition and Physical Activity on Telomere Length.

Purpose of review: The number and proportion of individuals aged 60 and over are increasing globally. The increase in the elderly population has important social and economic effects. Telomere length is an important marker for healthy aging. Here, we review the relevance between telomere length and energy balance by determining the effects of physical activity, nutrients, dietary patterns, and foods on healthy aging and telomere length with related studies.

Recent findings: Evidence emphasizes the importance of telomere length and integrity for healthy aging. It also focuses on the importance of potential interventions such as physical activity and a healthy diet to improve this process. We suggest that ensuring energy balance with regular physical activity and healthy diets can contribute to the aging process by protecting telomere length. In addition, different methods in studies, short and inconsistent durations, different types of exercise, different diet patterns, and non-standard foods have led to conflicting results. More studies are needed to elucidate molecular-based mechanisms.

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来源期刊
Current Nutrition Reports
Current Nutrition Reports Agricultural and Biological Sciences-Food Science
CiteScore
7.70
自引率
2.00%
发文量
59
期刊介绍: This journal aims to provide comprehensive review articles that emphasize significant developments in nutrition research emerging in recent publications. By presenting clear, insightful, balanced contributions by international experts, the journal intends to discuss the influence of nutrition on major health conditions such as diabetes, cardiovascular disease, cancer, and obesity, as well as the impact of nutrition on genetics, metabolic function, and public health. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas across the field. Section Editors select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. We also provide commentaries from well-known figures in the field, and an Editorial Board of more than 25 internationally diverse members reviews the annual table of contents, suggests topics of special importance to their country/region, and ensures that topics and current and include emerging research.
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