通过计算深入了解 N-乙酰甘露糖胺激酶突变的动力学和构象稳定性

Ashraf B. Abdel-Naim, Pawan Kumar, Mohammed A. Bazuhair, Waleed Y. Rizg, Hatoon A. Niyazi, Khalil Alkuwaity, Hanouf A. Niyazi, Saif A. Alharthy, Steve Harakeh, Shafiul Haque, Amresh Prakash, Vijay Kumar
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引用次数: 0

摘要

UDP-GlcNAc 2-epimerase/ManNAc 激酶(GNE)的活性对于参与健康和疾病中细胞过程的硅酸的生物合成至关重要。GNE 含有一个 N-末端...
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Computational insights into dynamics and conformational stability of N-acetylmannosamine kinase mutations
The activity of UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE) is essential for the biosynthesis of sialic acid, which is involved in cellular processes in health and diseases. GNE contains an N-termin...
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