利用增强型分割和基于深度渐进学习的技术改进 PAP 涂片图像中的宫颈癌分类。

IF 1 4区 医学 Q4 MEDICAL LABORATORY TECHNOLOGY Diagnostic Cytopathology Pub Date : 2024-03-22 DOI:10.1002/dc.25295
Priyanka Mahajan PhD, Prabhpreet Kaur PhD
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引用次数: 0

摘要

目的:宫颈癌是妇女中一种常见的致命疾病,死亡率仅次于乳腺癌,每天有 700 多人死于宫颈癌。子宫颈抹片检查是一种广泛使用的早期宫颈癌筛查方法。然而,由于人为失误,这种人工筛查过程很容易出现高假阳性结果。研究人员正在利用计算机辅助诊断工具中的机器学习和深度学习来解决这一问题。这些工具可自动分析和分类宫颈细胞学检查和阴道镜检查图像,提高识别不同阶段宫颈癌的精确度:本文采用最先进的深度学习方法,如 ResNet-50 对宫颈癌细胞进行分类,以帮助医疗专业人员。该方法包括三个关键步骤:预处理、使用 k-means 聚类进行分割以及对癌细胞进行分类。该模型根据精确度、准确度、卡帕得分、精确度、灵敏度和特异性等性能指标进行评估。最终,高成功率表明 ResNet50 模型是及时检测宫颈癌的重要工具:总之,通过空间 K 均值聚类和预处理操作,确定了受感染的宫颈区域。这一系列操作之后是渐进学习技术。渐进式学习技术分为几个阶段:第 1 阶段使用 64 × 64 图像,第 2 阶段使用 224 × 224 图像,第 3 阶段使用 512 × 512 图像,最后第 4 阶段使用 1024 × 1024 图像。结果表明,建议的模型能有效分析巴氏涂片检验,准确率达到 97.4%,卡帕得分率约为 98%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Improving cervical cancer classification in PAP smear images with enhanced segmentation and deep progressive learning-based techniques

Objective

Cervical cancer, a prevalent and deadly disease among women, comes second only to breast cancer, with over 700 daily deaths. The Pap smear test is a widely utilized screening method for detecting cervical cancer in its early stages. However, this manual screening process is prone to a high rate of false-positive outcomes because of human errors. Researchers are using machine learning and deep learning in computer-aided diagnostic tools to address this issue. These tools automatically analyze and sort cervical cytology and colposcopy images, improving the precision of identifying various stages of cervical cancer.

Methodology

This article uses state-of-the-art deep learning methods, such as ResNet-50 for categorizing cervical cancer cells to assist medical professionals. The method includes three key steps: preprocessing, segmentation using k-means clustering, and classifying cancer cells. The model is assessed based on performance metrics viz; precision, accuracy, kappa score, precision, sensitivity, and specificity. In the end, the high success rate shows that the ResNet50 model is a valuable tool for timely detection of cervical cancer.

Outputs

In conclusion, the infected cervical region is pinpointed using spatial K-means clustering and preprocessing operations. This sequence of actions is followed by a progressive learning technique. The Progressive Learning technique then proceeded through several stages: Stage 1 with 64 × 64 images, Stage 2 with 224 × 224 images, Stage 3 with 512 × 512 images, and the final Stage 4 with 1024 × 1024 images. The outcomes show that the suggested model is effective for analyzing Pap smear tests, achieving 97.4% accuracy and approx. 98% kappa score.

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来源期刊
Diagnostic Cytopathology
Diagnostic Cytopathology 医学-病理学
CiteScore
2.60
自引率
7.70%
发文量
163
审稿时长
3-6 weeks
期刊介绍: Diagnostic Cytopathology is intended to provide a forum for the exchange of information in the field of cytopathology, with special emphasis on the practical, clinical aspects of the discipline. The editors invite original scientific articles, as well as special review articles, feature articles, and letters to the editor, from laboratory professionals engaged in the practice of cytopathology. Manuscripts are accepted for publication on the basis of scientific merit, practical significance, and suitability for publication in a journal dedicated to this discipline. Original articles can be considered only with the understanding that they have never been published before and that they have not been submitted for simultaneous review to another publication.
期刊最新文献
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