Patrycja Krolewska-Daszczynska, Marta Smycz-Kubanska, Celina Kruszniewska-Rajs, Jacek Kabut, Paweł Olczyk, Joanna Gola, Aleksandra Mielczarek-Palacz
{"title":"评估乳腺癌女性患者体内肿瘤细胞抗体的潜在流行率。","authors":"Patrycja Krolewska-Daszczynska, Marta Smycz-Kubanska, Celina Kruszniewska-Rajs, Jacek Kabut, Paweł Olczyk, Joanna Gola, Aleksandra Mielczarek-Palacz","doi":"10.36740/Merkur202401101","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Aim: To analyse onconeural antibodies in the blood serum of breast cancer patients without neurological symptoms..</p><p><strong>Patients and methods: </strong>Materials and Methods: The study included 48 women with breast cancer. Paraneoplastic Neurologic Syndromes 12 Ag (IgG) Euroline by EUROIMMUN test was used to determine onconeural antibodies: anti-Hu, anti-Yo, anti-Ri, anti-CV2, anti-Ma/anti-Ta, anti-amphiphysin, anti-recoverin, anti-SOX1, anti-tytin, anti-zic4, anti-GAD65 and anti-Tr (DNER).</p><p><strong>Results: </strong>Results: The conducted analysis revealed the presence of onconeural antibodies such as: anti-recoverin, anti-CV2, anti-Zic4, anti-SOX1, anti-MA2/Ta and antititin in blood serum of women with breast cancer.</p><p><strong>Conclusion: </strong>Conclusions: Further analysis may allow the assessment of the possible clinical usefulness of these determinations.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"52 1","pages":"5-9"},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Evaluation of potential prevalence of onconeural antibodies in women with breast cancer.\",\"authors\":\"Patrycja Krolewska-Daszczynska, Marta Smycz-Kubanska, Celina Kruszniewska-Rajs, Jacek Kabut, Paweł Olczyk, Joanna Gola, Aleksandra Mielczarek-Palacz\",\"doi\":\"10.36740/Merkur202401101\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>Aim: To analyse onconeural antibodies in the blood serum of breast cancer patients without neurological symptoms..</p><p><strong>Patients and methods: </strong>Materials and Methods: The study included 48 women with breast cancer. Paraneoplastic Neurologic Syndromes 12 Ag (IgG) Euroline by EUROIMMUN test was used to determine onconeural antibodies: anti-Hu, anti-Yo, anti-Ri, anti-CV2, anti-Ma/anti-Ta, anti-amphiphysin, anti-recoverin, anti-SOX1, anti-tytin, anti-zic4, anti-GAD65 and anti-Tr (DNER).</p><p><strong>Results: </strong>Results: The conducted analysis revealed the presence of onconeural antibodies such as: anti-recoverin, anti-CV2, anti-Zic4, anti-SOX1, anti-MA2/Ta and antititin in blood serum of women with breast cancer.</p><p><strong>Conclusion: </strong>Conclusions: Further analysis may allow the assessment of the possible clinical usefulness of these determinations.</p>\",\"PeriodicalId\":39518,\"journal\":{\"name\":\"Polski Merkuriusz Lekarski\",\"volume\":\"52 1\",\"pages\":\"5-9\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Polski Merkuriusz Lekarski\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.36740/Merkur202401101\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polski Merkuriusz Lekarski","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36740/Merkur202401101","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Evaluation of potential prevalence of onconeural antibodies in women with breast cancer.
Objective: Aim: To analyse onconeural antibodies in the blood serum of breast cancer patients without neurological symptoms..
Patients and methods: Materials and Methods: The study included 48 women with breast cancer. Paraneoplastic Neurologic Syndromes 12 Ag (IgG) Euroline by EUROIMMUN test was used to determine onconeural antibodies: anti-Hu, anti-Yo, anti-Ri, anti-CV2, anti-Ma/anti-Ta, anti-amphiphysin, anti-recoverin, anti-SOX1, anti-tytin, anti-zic4, anti-GAD65 and anti-Tr (DNER).
Results: Results: The conducted analysis revealed the presence of onconeural antibodies such as: anti-recoverin, anti-CV2, anti-Zic4, anti-SOX1, anti-MA2/Ta and antititin in blood serum of women with breast cancer.
Conclusion: Conclusions: Further analysis may allow the assessment of the possible clinical usefulness of these determinations.
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