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引用次数: 0
摘要
研究背景本研究的目的是评估老年双相情感障碍 I 患者与健康人相比的社会心理功能,并确定与患者功能低下相关的心理病理因素:我们从门诊部招募了 68 名躁狂症 I 患者和 89 名年龄在 50 岁以上的健康对照者。除临床变量外,我们还使用了其他标准化测量方法,包括青年躁狂评定量表、汉密尔顿抑郁评定量表、汉密尔顿焦虑评定量表、功能评估短测试和蒙特利尔认知评估:结果:与健康对照组相比,根据之前定义的功能评估简短测试临界分数,双相情感障碍 I 老年患者的总体社会心理功能以及职业、自主性和认知领域的社会心理功能均较差。我们发现,35.3%(95% CI:23%-47%)的患者没有明显的临床功能障碍,38.2%(95% CI:26%-50%)的患者有轻度功能障碍,26.5%(95% CI:16%-37%)的患者有中度功能障碍。抑郁症状和认知能力受损与整体功能低下有关:结论:患者的社会心理功能水平参差不齐。抑郁症状(即使程度较轻)和认知功能受损预示着躁狂症 I 型中老年患者的功能较差。
Psychosocial Impairment in Older Patients With Bipolar I Disorder.
Background: The goal of this study was to assess psychosocial functioning in older patients with bipolar I disorder compared with healthy subjects and to identify the psychopathological factors associated with poor functioning in patients.
Methods: We recruited 68 euthymic patients with bipolar I disorder from the outpatient unit and 89 healthy controls who were older than 50 years of age. In addition to clinical variables, we used other standardized measures, including the Young Mania Rating Scale, the Hamilton Depression Rating Scale, the Hamilton Anxiety Rating Scale, the Functional Assessment Short Test, and the Montreal Cognitive Assessment.
Results: Older patients with bipolar I disorder had poorer psychosocial functioning in general and in the domains of occupation, autonomy, and cognition than the healthy controls on the basis of previously defined Functional Assessment Short Test cutoff scores. We found that 35.3% (95% CI: 23%-47%) of the patients did not have clinically significant functional impairment, 38.2% (95% CI: 26%-50%) had mild impairment, and 26.5% (95% CI: 16%-37%) had moderate impairment. Depressive symptoms and impaired cognition were associated with poor overall functioning.
Conclusions: The level of psychosocial functioning was heterogeneous among the patients. Subsyndromal depressive symptoms, even at low levels, and impaired cognition predicted poor functioning in euthymic middle-aged and older patients with bipolar I disorder.
期刊介绍:
Journal of Psychiatric Practice® seizes the day with its emphasis on the three Rs — readability, reliability, and relevance. Featuring an eye-catching style, the journal combines clinically applicable reviews, case studies, and articles on treatment advances with practical and informative tips for treating patients. Mental health professionals will want access to this review journal — for sharpening their clinical skills, discovering the best in treatment, and navigating this rapidly changing field.
Journal of Psychiatric Practice combines clinically applicable reviews, case studies, and articles on treatment advances with informative "how to" tips for surviving in a managed care environment.