Aleksandra Jartych, A. Jamróz-Wiśniewska, Konrad Rejdak, Weronika Kleszczyńska, Michał Kaczor
{"title":"一例并发幼年特发性关节炎(JIA)和儿童型多发性硬化症(POMS)的病例--先用secukinumab和富马酸二甲酯治疗,再用ofatumumab治疗","authors":"Aleksandra Jartych, A. Jamróz-Wiśniewska, Konrad Rejdak, Weronika Kleszczyńska, Michał Kaczor","doi":"10.26444/jpccr/185685","DOIUrl":null,"url":null,"abstract":"The aim of this case report is to highlight new possible treatment methods for concomitant juvenile idiopathic arthritis and multiple sclerosis in young patients. Promising results of using ofatumumab, secukinumab and dimethyl fumarate, both in the clinical case of a 22-year-old patient and mentioned literature, allows the belief that there is a chance for improving the quality of life of those who suffer from coexisting autoimmune diseases. However, it is crucial to perform further research in terms of the necessity and safety of the mentioned therapies, especially in the paediatric population, among whom there often exists difficulty in using treatment not registered for under-aged patients. Furthermore, the higher risk of side-effects caused by combined treatment of two autoimmune diseases should also be taken into consideration.","PeriodicalId":16886,"journal":{"name":"Journal of Pre-Clinical and Clinical Research","volume":"53 7","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A case of concomitant juvenile idiopathic arthritis (JIA) and paediatric-onset multiple sclerosis (POMS) – treatment with secukinumab and dimethyl fumarate followed by ofatumumab\",\"authors\":\"Aleksandra Jartych, A. Jamróz-Wiśniewska, Konrad Rejdak, Weronika Kleszczyńska, Michał Kaczor\",\"doi\":\"10.26444/jpccr/185685\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The aim of this case report is to highlight new possible treatment methods for concomitant juvenile idiopathic arthritis and multiple sclerosis in young patients. Promising results of using ofatumumab, secukinumab and dimethyl fumarate, both in the clinical case of a 22-year-old patient and mentioned literature, allows the belief that there is a chance for improving the quality of life of those who suffer from coexisting autoimmune diseases. However, it is crucial to perform further research in terms of the necessity and safety of the mentioned therapies, especially in the paediatric population, among whom there often exists difficulty in using treatment not registered for under-aged patients. Furthermore, the higher risk of side-effects caused by combined treatment of two autoimmune diseases should also be taken into consideration.\",\"PeriodicalId\":16886,\"journal\":{\"name\":\"Journal of Pre-Clinical and Clinical Research\",\"volume\":\"53 7\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-03-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pre-Clinical and Clinical Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.26444/jpccr/185685\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pre-Clinical and Clinical Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26444/jpccr/185685","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A case of concomitant juvenile idiopathic arthritis (JIA) and paediatric-onset multiple sclerosis (POMS) – treatment with secukinumab and dimethyl fumarate followed by ofatumumab
The aim of this case report is to highlight new possible treatment methods for concomitant juvenile idiopathic arthritis and multiple sclerosis in young patients. Promising results of using ofatumumab, secukinumab and dimethyl fumarate, both in the clinical case of a 22-year-old patient and mentioned literature, allows the belief that there is a chance for improving the quality of life of those who suffer from coexisting autoimmune diseases. However, it is crucial to perform further research in terms of the necessity and safety of the mentioned therapies, especially in the paediatric population, among whom there often exists difficulty in using treatment not registered for under-aged patients. Furthermore, the higher risk of side-effects caused by combined treatment of two autoimmune diseases should also be taken into consideration.