以复合疗法为背景,评估伴有非酒精性脂肪肝的足癣和霉菌病患者的生活质量

G. Rustamkhanova, Z. R. Hismatullina, N.A. Vlasova, D. Gashimova
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摘要

研究背景目前,人们非常关注病人的质量,这是一个有希望的生活方向,可以全面客观地了解疾病,确定最稳定的治疗方法,并评估其结果。目的使用改良的生活质量综合指数(QL-Index)问卷调查表,评估复合疗法对伴有非酒精性重度肝病(NAFLD)的足癣和霉菌病患者的疗效。方法。对同时患有非酒精性重度肝病的足癣和霉菌病患者进行综合治疗前后的生活质量综合指数(QL-Index)测定。结果显示对 117 名伴有非酒精性脂肪肝的足癣和足部霉菌病患者进行治疗前生活质量综合指数评估的结果分析表明,大多数受访者(69.2%)的足癣和足部霉菌病对其生活有很大影响。复合治疗后,根据生活质量指数联合问卷调查结果显示,伴有非酒精性脂肪肝的甲癣和足部霉菌病患者的社会活动增加,心理情绪得到改善。患者的生活质量得到了改善,这大大提高了这一复杂治疗的效果。结论对伴有非酒精性脂肪肝的甲真菌病和足部真菌病患者采用复合疗法,包括全身抗真菌药物伊曲康唑与外用抗真菌药物、保肝药和益生元联合使用,疗效显著,安全性高。
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Assessment of the quality of life in patients with onychomycosis and mycosis of the feet with concomitant non-alcoholic fatty liver disease against the background of complex therapy
Background. Сurrently, much attention is paid to the quality of patients, which is a promising direction of life, allowing to put a complete and objective picture of the disease, determine the most stable method of treatment, and evaluate its results. Aims. To evaluate the effectiveness of complex therapy in patients with onychomycosis and mycosis of the feet with concomitant non-alcoholic severe liver disease (NAFLD) using a modified questionnaire-questionnaire of the combined index of quality of life (QL-Index). Methods. The combined index of quality of life (QL-Index) was determined in patients with onychomycosis and mycosis of the feet with with concomitant NAFLD before and after complex therapy. Results. Analysis of the results of assessing the presence of a combined index of quality of life in 117 patients with onychomycosis and foot mycosis with concomitant NAFLD before treatment showed that the presence of onychomycosis and mycosis of the feet in the majority of respondents has a strong impact on the lives of the respondents (69.2%). After the complex treatment, according to the results of the combined questionnaire-questionnaire of the quality of life index, it was revealed that social activity in patients with onychomycosis and foot mycosis with concomitant NAFLD increased, and the psycho-emotional state improved. The quality of life of patients has improved, which significantly increased the effectiveness of this complex treatment. Conclusion. The high efficacy and safety of complex therapy, which included the use of the systemic antimycotic itraconazole in combination with external antifungal drugs, a hepatoprotector and a prebiotic in patients with onychomycosis and mycosis of the feet with concomitant NAFLD.
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