慢性肾病患者和非慢性肾病患者的维生素 D 水平、临床和流行病学概况:厄瓜多尔基多一家二级医院的初步分析。

André Benítez-Baldassari, Estefanía León-Hernández, Andrea Banegas-Sarmiento, Santiago Aguayo-Moscoso, J. Vélez-Páez
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摘要

维生素 D 具有与骨矿物质代谢无关的各种作用,例如与动脉高血压有关。本研究确定了厄瓜多尔患者维生素 D 缺乏和不足的患病情况、流行病学特征及其与其他疾病(如动脉高血压、糖尿病和慢性肾病)的关系。这是厄瓜多尔的一项开创性回顾性研究,该研究在巴勃罗-阿图罗-苏亚雷斯医院进行,历时 6 个月。同样,我们还证实了维生素D水平与年龄之间的反比关系,并发现维生素D水平与动脉高血压之间存在一定的联系;而维生素D水平与糖尿病、未使用肾脏替代疗法的慢性肾脏病以及普通人群之间的关系则没有发现显著差异。
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Niveles de Vitamina D en pacientes con y sin Enfermedad Renal Crónica, perfil clínico y epidemiológico: un análisis preeliminiar en un hospital de segundo nivel en quito, Ecuador.
Vitamin D has been associated with different effects unrelated to bone-mineral metabolism, such as its association with arterial hypertension. This study determines the prevalence profile of vitamin D deficiency and insufficiency in Ecuadorian patients, its epidemiological profile, and its relationship with other diseases such as arterial hypertension, diabetes mellitus, and chronic kidney disease. This is a pioneering study in Ecuador of a retrospective type, carried out at the Pablo Arturo Suarez Hospital over 6 months, in which it was found that the prevalence of vitamin D insufficiency was 28.5% (levels between 21 to 30 ng/ml) and deficiency was 57% (levels less than 20 ng/ml); Likewise, we ratify the inverse relationship between vitamin D levels and age, as well as finding a certain association between vitamin D levels and the presence of arterial hypertension; while no significant differences were found in its relationship with diabetes mellitus, chronic kidney disease without the use of renal replacement therapy and the general population. Keywords: vitamin D, chronic kidney disease, metabolism.
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