饮食干预对 1 型糖尿病患者胰岛素需求和血糖控制的影响：为期 12 周的随机临床试验

Q2 Medicine Clinical Diabetes Pub Date : 2024-03-14 DOI:10.2337/cd23-0086

H. Kahleová, Tatiana Znayenko-Miller, Karen Smith, Cyrus Khambatta, Robby Barbaro, Macy Sutton, D. Holtz, Mark Sklar, Desiree Pineda, Richard Holubkov, Neal D. Barnard

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引用次数: 0

摘要

这项研究比较了低脂素食与控制饮食份量对 1 型糖尿病患者的影响。在 12 周的时间里，素食组的胰岛素日平均总剂量显著下降，胰岛素敏感性显著提高，而接受控制饮食份量组则没有观察到明显变化。素食组的总胆固醇和低密度脂蛋白胆固醇下降，血尿素氮与肌酐的比率也有所下降。两组的 A1C 都有所下降。这些研究结果表明，与控制份量的饮食相比，低脂素食可能会改善 1 型糖尿病患者的胰岛素敏感性、胰岛素需求量、血糖控制以及心血管和肾脏健康指标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Effect of a Dietary Intervention on Insulin Requirements and Glycemic Control in Type 1 Diabetes: A 12-Week Randomized Clinical Trial

This study compared the effects of a low-fat vegan diet to those of a portion-controlled diet in people with type 1 diabetes. Over 12 weeks, the average total daily dose of insulin decreased significantly and insulin sensitivity increased significantly in the vegan group, while no significant changes were observed in the group receiving the portion-controlled diet. Total and LDL cholesterol decreased in the vegan group, as did the ratio of blood urea nitrogen to creatinine. A1C decreased in both groups. These findings suggest that a low-fat vegan diet may yield improvements in insulin sensitivity, insulin requirements, glycemic control, and markers of cardiovascular and renal health compared with a portion-controlled diet in people with type 1 diabetes.

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来源期刊

Clinical Diabetes Medicine-Internal Medicine

CiteScore

4.30

自引率

0.00%

发文量

期刊介绍： The mission of Clinical Diabetes is to provide primary care providers and all clinicians involved in the care of people with diabetes with information on advances and state-of-the-art care for people with diabetes. Clinical Diabetes is also a forum for discussing diabetes-related problems in practice, medical-legal issues, case studies, digests of recent research, and patient education materials.