坦桑尼亚达累斯萨拉姆 Kinondoni 市部分医疗机构的成人对儿童接种 COVID-19 疫苗的接受程度:横断面研究

Nashon Mugobera, Leonard Malasa, Dharia Amour, Maulid Fataki, F. Rutachunzibwa, F. S. Kalabamu
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摘要

背景:安全有效的疫苗对于控制和遏制 COVID-19 大流行至关重要。然而,对疫苗的接受度低和犹豫不决限制了疫苗的有效使用。在坦桑尼亚,COVID-19 疫苗已在 18 岁以上的成年人中得到充分使用,但儿童对其使用的接受度却不甚了解。本研究旨在确定坦桑尼亚达累斯萨拉姆成人对儿童接种 COVID-19 疫苗的接受程度。 方法:这项横断面研究的对象是在达累斯萨拉姆门诊就诊且家中有 18 岁以下儿童的成年人。研究采用自填问卷的方式收集他们的人口统计学信息以及他们对子女接种 COVID-19 疫苗的看法。数据使用社会科学统计软件包(SPSS 23 版)进行分析。接受程度和其他分类变量以频率和百分比计算,而与儿童接种 COVID-19 疫苗相关的因素则采用二元逻辑回归分析法确定。 小于或等于 0.05 的 II 型误差被认为具有统计学意义。 结果:研究共招募了 320 名参与者。其中 289 人(90.3%)为女性。在所有参与者中,124人(38.57%)愿意让他们的孩子接种COVID-19疫苗,前提是疫苗可用并得到相关部门的推荐。对 COVID-19 疫苗安全性的信心(调整后奇数比= 0.03;95% CI:0.01-0.13;P=0.02)和认为 COVID-19 疫苗在儿童中使用的重要性(AOR=0.29;95% CI:0.1-0.84;P=0.02)是儿童接受 COVID-19 疫苗接种的独立相关因素。 结论:在本研究中,儿童对接种 COVID-19 疫苗的接受程度较低(38.57%),疫苗安全性的不确定性是主要担忧。因此,为了提高儿童对 COVID-19 疫苗的接受度和接种率,应强调在 COVID-19 疫苗安全性和有效性数据的支持下进行有效的公众沟通。
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Acceptance of COVID-19 Vaccination in Children among Adults attending Selected Health Facilities in Kinondoni Municipality; Dar es salaam, Tanzania: A Cross Sectional Study
BACKGROUND: Safe and effective vaccines are crucial for controlling and containing COVID-19 pandemic. However, poor acceptance and hesitance to vaccinate limit effective utilization. In Tanzania, COVID-19 vaccines have been in use with adequate coverage in adults from 18-years old, however, the acceptability of their use in children is not well understood. This study was aimed at determining the acceptability of COVID-19 vaccination in children among adults in Dar es salaam, Tanzania. METHODS: A cross section study was conducted among adults attending outpatient clinic in Dar es salaam and were having children below 18-years at home. A self-administered questionnaire was used to collect their demographic information and their opinions regarding COVID-19 vaccine use in their children. Data was analyzed using Statistical Package for Social Sciences (SPSS version 23). Level of acceptance and other categorical variables were calculated in frequency and percentages while factors associated with COVID-19 vaccination in children were determined using binary logistic regression analysis.  A type II error of less or equal to 0.05 was considered statistically significant. RESULTS: A total of 320 participants were recruited in the study. Among these, 289 (90.3%) were females. Out of all participants, 124 (38.57%) were willing for their children to receive COVID-19 vaccines upon availability and recommendation by respective authorities. Confidence in the safety of COVID-19 vaccines (Adjusted Odd Ratio= 0.03; 95% CI: 0.01-0.13; p=0.02, and perceived importance of COVID-19 vaccine use in children (AOR=0.29; 95% CI: 0.1-0.84; p=0.02) were independent factors associated with acceptance of COVID-19 vaccination in children. CONCLUSION: The level of acceptance of COVID-19 vaccination for children in this study was low (38.57%), with uncertainty around vaccine safety being the major concern. Therefore, to increase COVID-19 vaccines acceptance and uptake in children, effective public communication supported by data on safety and effectiveness of COVID-19 vaccines should be emphasized. 
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