儿科心肌炎:巴基斯坦医疗系统日益关注的问题

S. Ilyas, M. Bilal
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Moreover, long-term consequences can manifest as chronic heart failure, which necessitates continuous, ongoing monitoring and management to optimize cardiac function and quality of life (Upadhya and Kitzman, 2020). We have noticed a worrying trend in our pediatric cardiology practice at Lady Reading Hospital Peshawar, whereby approximately half of the patients who consult our outpatient and inpatient departments have left ventricular failure. A significant portion of these cases are diagnosed as viral myocarditis. We have noticed a worrying trend in our pediatric cardiology practice: about 50% of the cases that come into our outpatient and inpatient departments have left ventricular failure, and a sizable percentage of those cases are diagnosed with myocarditis. 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引用次数: 0

摘要

心肌炎被定义为心肌的炎症,由于其病因多样且可能造成严重后果,因此给儿科心脏病学带来了巨大挑战。虽然心肌炎有几种潜在的病因,例如自身免疫性疾病和毒素,但病毒感染占儿科病例的绝大多数(Tschöpe et al.)由于病毒性疾病在儿童中的发病率增加,尤其是在特定季节,心肌炎的发病率仍然相当高;这给医院资源造成了巨大压力。儿科心肌炎对心脏造成的后果不仅仅是最初的炎症损伤。心肌炎患者通常会出现急性心力衰竭、心律失常,严重时还会导致心源性休克(Ammirati 等人,2021 年)。此外,长期后果可能表现为慢性心力衰竭,这就需要持续不断地进行监测和管理,以优化心脏功能和生活质量(Upadhya 和 Kitzman,2020 年)。我们在白沙瓦雷丁夫人医院的儿科心脏病学实践中注意到一个令人担忧的趋势,即在门诊和住院部就诊的患者中,约有一半患有左心室衰竭。其中很大一部分病例被诊断为病毒性心肌炎。在我们的儿科心脏病学实践中,我们发现了一个令人担忧的趋势:在我们的门诊和住院部就诊的病例中,约有 50%患有左心室功能衰竭,其中相当一部分病例被诊断为心肌炎。这一发现不仅突显了心肌炎的发病率,而且还强调了提高对病毒性心肌炎的认识、及时诊断和有效管理的迫切需要,以减少对弱势儿科人群的负面影响。在巴基斯坦这样资源匮乏的环境中,心肌炎的治疗面临着独特的挑战。静脉注射免疫球蛋白等治疗方法虽然在某些患者身上取得了成功,但通常价格昂贵,且不易获得(Ammirati 等人,2021 年)。在获得现代治疗方法方面存在的差距会进一步加重医疗系统的负担,而医疗系统本已因心肌炎的高发病率而不堪重负。在巴基斯坦这样的中低收入国家(LMICs),积极的预防性干预措施对于减轻已经不堪重负的医疗系统的压力尤为重要。通过强调接种与腺病毒和肠道病毒等常见病毒感染有关的疫苗的重要性,可以降低儿童心肌炎的发病率(Makimaa 等人,2020 年;Upadhya 和 Kitzman,2020 年)。此外,提高护理人员和医疗专业人员对早期发现心肌炎症状的认识,以及及时将患者转诊到专科诊所的重要性,将有助于加快干预并提高长期疗效(Inoue 等人,2019 年)。总之,儿科心肌炎的发病率越来越高,需要采取包括早期检测、预防和完整治疗技术在内的多模式策略。通过共同解决这些问题并推动公平获得关键治疗,我们可以设法减轻心肌炎对儿科心脏健康的影响,减轻医疗系统的负担,尤其是在资源有限的环境中。
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MYOCARDITIS IN PEDIATRICS: A GROWING CONCERN FOR HEALTHCARE SYSTEMS IN PAKISTAN
Myocarditis, defined as an inflammation of the heart muscle, can pose significant challenges in pediatric cardiology due to its varied causes and potentially serious consequences. While there are several potential causes of myocarditis, for instance, autoimmune diseases and toxins, viral infections account for a large majority of cases in pediatric populations (Tschöpe et al., 2021). The frequency of myocarditis is still rather high due to the increased prevalence of viral diseases in children, especially during specific seasons; this puts a significant strain on hospital resources. Myocarditis in paediatric patients has consequences that go beyond the initial inflammatory insult to the heart. Patients affected with myocarditis can often exhibit acute heart failure, arrhythmias, and, in severe cases, cardiogenic shock (Ammirati et al., 2021). Moreover, long-term consequences can manifest as chronic heart failure, which necessitates continuous, ongoing monitoring and management to optimize cardiac function and quality of life (Upadhya and Kitzman, 2020). We have noticed a worrying trend in our pediatric cardiology practice at Lady Reading Hospital Peshawar, whereby approximately half of the patients who consult our outpatient and inpatient departments have left ventricular failure. A significant portion of these cases are diagnosed as viral myocarditis. We have noticed a worrying trend in our pediatric cardiology practice: about 50% of the cases that come into our outpatient and inpatient departments have left ventricular failure, and a sizable percentage of those cases are diagnosed with myocarditis. This finding not only highlights the frequency of myocarditis but also highlights the pressing need for increased awareness, prompt diagnosis, and effective management of viral myocarditis in order to reduce negative consequences in vulnerable pediatric populations. In resource-poor environments like Pakistan managing myocarditis can unique challenges. Treatment methods such as IV immunoglobulin treatment which can have proven success in some patients, are generally expensive and not readily available (Ammirati et al., 2021). This gap in access to modern treatments can further exacerbate the load on healthcare systems that are already strained by the high prevalence of myocarditis. In low and middle-income countries (LMICs) like Pakistan, proactive preventative interventions are especially important to reduce the strain on already overburdened healthcare systems. The increased frequency of myocarditis in pediatric populations can be decreased by highlighting the significance of vaccination against common viral infections linked to the illness such as adenovirus and enterovirus (Makimaa et al., 2020; Upadhya and Kitzman, 2020). In addition, raising awareness among caregivers and medical professionals about the early detection of myocarditis symptoms and the importance of promptly referring patients to specialized clinics will help to expedite intervention and enhance long-term results (Inoue et al., 2019). In summary, the growing incidence of myocarditis in pediatric patients demands a multimodal strategy that includes early detection, prevention, and complete therapeutic techniques. By addressing these issues collectively and pushing for fair access to key treatments, we can seek to lessen the impact of myocarditis on pediatric cardiac health and alleviate the load on healthcare systems, particularly in resource-limited settings.
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