拉瓦尔品第和伊斯兰堡疑似伤寒病例流行病学研究:对公共卫生干预的影响

S. Yasmeen, T. Parveen, K. Nazar
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引用次数: 0

摘要

伤寒仍然是巴基斯坦的一个重大公共卫生问题,尤其是在拉瓦尔品第和伊斯兰堡等城市地区。了解这种疾病的流行情况对于为公共卫生干预措施和资源分配提供信息至关重要。本研究旨在确定拉瓦尔品第和伊斯兰堡地区疑似伤寒患者的患病率。这项横断面研究从 2011 年 11 月至 2012 年 1 月进行,历时三个月。研究人员从各地区医院和临床实验室随机抽取了 500 名伤寒疑似患者。样本采用威达检测法或伤寒杆菌点检测法进行检测,并记录了患者人口统计学数据和检测结果。描述性统计(包括频率和百分比)用于总结数据。计算患病率,并进行分组分析,以探讨不同年龄组患病率的差异。在收集到的 500 份样本中,95 份样本的伤寒检测呈阳性,总患病率为 19%。分组分析显示,31.5%的阳性病例为成人,68.5%为15岁以下儿童。在儿童中,不同年龄组的流行率各不相同,1-4 岁、5-12 岁和 12-15 岁的阳性病例分别占 13.8%、55.3% 和 30.7%。进一步分析估算了拉瓦尔品第和伊斯兰堡的伤寒总发病率,结果显示儿童中的发病率为每万人 685 例。这项研究凸显了伤寒给拉瓦尔品第和伊斯兰堡带来的沉重负担,尤其是在儿童中。研究结果突出表明,必须采取有针对性的干预措施来控制疾病的传播,包括开展疫苗接种活动和改善卫生措施。持续的监视和监测对于跟踪伤寒流行趋势和指导区域公共卫生战略至关重要。
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EPIDEMIOLOGICAL STUDY OF TYPHOID FEVER PREVALENCE AMONG SUSPECTED CASES IN RAWALPINDI AND ISLAMABAD: IMPLICATIONS FOR PUBLIC HEALTH INTERVENTION
Typhoid fever remains a significant public health concern in Pakistan, particularly in urban areas such as Rawalpindi and Islamabad. Understanding the prevalence of this disease is crucial for informing public health interventions and resource allocation. This study aims to determine the prevalence of typhoid fever among patients suspected of the disease in District Rawalpindi and Islamabad. A cross-sectional study was conducted over three months, from November 2011 to January 2012. A random sample of 500 patients suspected of typhoid fever was collected from various regional hospitals and clinical laboratories. Samples were tested using the Widal test or Typhi dot, and data on patient demographics and test results were recorded. Descriptive statistics, including frequencies and percentages, were used to summarize the data. Prevalence rates were calculated, and subgroup analyses were conducted to explore variations in prevalence among different age groups. Of the 500 samples collected, 95 tested positive for typhoid fever, yielding an overall prevalence rate of 19%. Subgroup analysis revealed that 31.5% of positive cases were in adults, while 68.5% were in children under the age of 15 years. Among children, the prevalence rates varied across different age groups, with 13.8%, 55.3%, and 30.7% of positive cases reported in 1-4 years, 5-12 years, and 12-15 years, respectively. Further analysis estimated the total prevalence of typhoid fever in Rawalpindi and Islamabad, revealing a prevalence rate of 685 per 10,000 individuals among children. This study highlights the significant burden of typhoid fever in Rawalpindi and Islamabad, particularly among children. The findings underscore the importance of targeted interventions to control the spread of the disease, including vaccination campaigns and improved sanitation measures. Continued surveillance and monitoring are essential for tracking trends in typhoid prevalence and guiding regional public health strategies.
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