改变癌细胞的电学、光学和磁学特性:癌症管理的综合方法

Medicine Advances Pub Date : 2024-03-08 DOI:10.1002/med4.51
Rishav Sharma, Rishabha Malviya
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引用次数: 0

摘要

尽管近年来癌症治疗取得了巨大成功,但仍然存在许多障碍。16 世纪的医学界认为,磁铁可以用来治疗或预防疾病。然而,这一理念直到最近才在癌症治疗中付诸实践。癌症不仅在患者、组织和细胞层面存在巨大差异,在分子层面也是如此。由于这种多尺度的异质性,很难开发出既能区分癌症组织和健康组织,又能针对各种肿瘤亚克隆的有效治疗方法。大多数治疗方法要么是利用癌细胞共有的特定生物特性(如快速分裂倾向),要么是不加区别地消灭相关区域的所有细胞。在本文中,我们将回顾癌细胞的物理、化学、电学、光学和磁学特性,然后讨论如何通过当前和未来的癌症疗法来调节这些特性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Modifying the electrical, optical, and magnetic properties of cancer cells: A comprehensive approach for cancer management

Despite the recent successes of cancer therapy, numerous obstacles remain. The medical community of the 16th century believed that magnets might be used to cure or prevent illness. However, this concept has only recently been put into practice in the treatment of cancer. Cancers vary greatly not only at the patient, tissue, and cellular levels but also at the molecular level. Because of this multiscale heterogeneity, effective treatments that not only differentiate between cancerous and healthy tissues but also target a wide variety of tumor subclones are difficult to develop. Most treatments either take advantage of a specific biological characteristic shared by cancer cells (e.g., their propensity for rapid division) or indiscriminately eradicate every cell in an area of interest. In this article, we review the physical, chemical, electrical, optical, and magnetic properties of cancer cells, before discussing how these properties may be modulated by current and future cancer therapies.

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