机器人辅助腹腔镜根治性前列腺切除术(Retzius Sparing Robotic Assisted Laparoscopic Radical Prostatectomy)的手术经验和结果:泰国首次报告

Tanet Thaidumrong, Sermsin Sindhubodee, Somjith Duangkae
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引用次数: 0

摘要

目的评估机器人辅助腹腔镜前列腺癌根治术(Retzius-sparing robot-assisted laparoscopic radical prostatectomy,RS-RALRP)的疗效和安全性,这在泰国尚属首次报道。材料与方法:作者对 Rajavithi 医院从 2021 年 1 月 1 日至 2023 年 5 月 31 日由一名外科医生实施 RS-RALRP 手术的 100 名患者的病历进行了回顾性分析。作者分析了人口统计学数据、临床分期、Gleason 等级组别、手术时间、病理分期、手术切缘阳性率、术后尿失禁恢复情况和术后并发症。结果显示中位年龄为(71.34±6.84)岁:平均总 PSA 为(17.16±17.55)纳克/毫升;临床分期大多为 T1 和 T2。平均手术时间为(221.7±51.93)分钟,平均失血量为(312.30±264.55)毫升。88%的患者无需输血。并发症发生率为 8%。病理分期为 pT2 和 pT3 或以上的患者分别占 62% 和 38%。手术切缘阳性(PSM)pT2和pT3分别为14.5%和63.2%。RS-RALRP术后1、3、6、9和12个月的尿失禁恢复率分别为83%、95%、97%、100%和100%。结论RS-RALRP有可能成为前列腺癌治疗的新标准,它能改善早期尿失禁情况,并具有同等的肿瘤疗效。这项研究的局限性在于受试者人数较少,因此需要进行前瞻性多中心研究。
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Surgical Experience and Results of Retzius Sparing Robotic Assisted Laparoscopic Radical Prostatectomy: First Report in Thailand
Objective: To evaluate the outcomes and safety of the surgical technique Retzius-sparing robot-assisted laparoscopic radical prostatectomy (RS-RALRP), with prostatic cancer; the first report in Thailand. Material and Methods: The authors conducted a retrospective analysis from the medical records of 100 patients who underwent RS-RALRP by a single surgeon; from 1st January 2021 until 31st May 2023, at Rajavithi Hospital. The authors analyzed demographic data, clinical staging, Gleason grade group, operative time, pathologic staging, positive surgical margin rate; postoperative continence recovery and postoperative complications. Results: The median age was 71.34±6.84 years: mean total PSA was 17.16±17.55 ng/ml; with the majority in clinical T1 and T2. The mean operative time was 221.7±51.93 minutes, and the mean estimated blood loss was 312.30±264.55 ml. Of all patients, 88% did not require blood transfusion. The complication rate was 8%. The pathologic stages pT2 and pT3 or greater were 62% and 38%, respectively. Positive surgical margins (PSM) pT2 and pT3 were 14.5% and 63.2%. The postoperative continence recovery after RS-RALRP were 83%, 95%, 97%,100% and 100%: at 1, 3, 6, 9 and 12 months postoperatively, respectively. Conclusion: RS-RALRP has a potential to become the new standard for prostate cancer treatment, with improved early continence and equivalent oncologic efficacy. The limitations of this study are the small number of population, which require prospective multicenter studies.
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