子宫肌瘤及其与黑人妇女的关系

João Pedro do Valle Varela, Shayenne Nogueira Domingues, Andressa Quimquim Samuel, Jacqueline Monfradini da Silva, Lucas Corrêa de Melo, Mariana Sasso Diniz, Gustavo Lorenzutti Teixeira, Elisa Spinassé Del Caro, Erick Cavaglieri Trevelin, Fabio Luiz Teixeira Fully
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摘要

子宫肌瘤是育龄妇女子宫内常见的良性肿瘤,可引起月经大量出血、盆腔疼痛和腹部体积增大等症状。研究表明,与其他种族的妇女相比,黑人妇女的子宫肌瘤发病率更高。了解造成这种差异的原因是制定更有效的预防和治疗策略的基础。本研究旨在调查子宫肌瘤发病率与黑人种族之间的关系,分析可能导致这种相关性的遗传和社会因素,并提出降低黑人妇女子宫肌瘤发病率的措施。本研究是一项系统性文献综述,采用探索性和叙述性方法,以定性和定量为前提。使用的数据库包括 PubMed、Scielo、Scopus、Web of Science 和虚拟健康图书馆。所分析的文章是根据排除和纳入标准(在此列出),使用 "子宫肌瘤"、"黑人妇女与子宫肌瘤"、"遗传因素与子宫肌瘤 "和 "环境因素与子宫肌瘤 "等健康科学描述词筛选出来的,共搜索到 617 篇文章,本研究使用了 9 篇。遗传学研究表明,黑人妇女有患子宫肌瘤的遗传倾向,并发现了与高风险相关的遗传变异。此外,社会因素,如获得优质医疗服务的机会有限、社会经济不平等和面临社会心理压力等,也可能起到重要作用。无法获得预防性医疗保健和无法平等地获得有效治疗可能是导致黑人妇女子宫肌瘤发病率较高的原因。减少这种差异的措施包括促进公平获得医疗保健、生殖健康教育以及解决健康不平等根本原因的公共政策。子宫肌瘤与黑人妇女之间的相关性突出表明,有必要采取综合方法,同时考虑遗传和社会因素。促进公平获得医疗保健和实施针对妇女健康的公共政策,是降低子宫肌瘤发病率和提高黑人妇女生活质量的关键。
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UTERINE FIBROIDS AND THE CORRELATION WITH BLACK WOMEN
Uterine fibroids are common benign tumors in the uterus of women of reproductive age and can cause symptoms such as heavy menstrual bleeding, pelvic pain and increased abdominal volume. Studies have shown a higher prevalence of uterine fibroids in black women compared to women of other ethnicities. Understanding the causes of this disparity is fundamental to developing more effective prevention and treatment strategies. Investigating the relationship between the incidence of uterine fibroids and black ethnicity, analyzing the genetic and social factors that may contribute to this correlation and proposing measures to reduce the incidence of uterine fibroids in black women are the aims of this study. This is a systematic literature review using an exploratory and narrative method, with qualitative and quantitative premises. The databases used were PubMed, Scielo, Scopus, Web of Science and the Virtual Health Library. The articles analyzed were selected by exclusion and inclusion criteria, which are set out here, using the health sciences descriptors “uterine fibroids”, “black women and uterine fibroids”, “genetic factors and uterine fibroids” and “environmental factors and uterine fibroids”, reaching a total of 617 articles searched and 9 used in this study. Genetic studies have suggested a genetic predisposition to the development of uterine fibroids in black women, with the identification of genetic variants associated with a higher risk. In addition, social factors such as limited access to quality healthcare, socioeconomic inequalities and exposure to psychosocial stressors may also play an important role. Lack of access to preventive healthcare and unequal access to effective treatments may contribute to a higher prevalence of uterine fibroids in black women. Measures to reduce this disparity include promoting equitable access to healthcare, reproductive health education and public policies that address the underlying causes of health inequalities. The correlation between uterine fibroids and black women highlights the need for integrated approaches that consider both genetic and social factors. Promoting equity in access to health care and implementing public policies aimed at women’s health are key to reducing the incidence of uterine fibroids and improving the quality of life of black women.
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