盐酸多巴胺液体选择性电极的构建

Rana A. Hammza
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摘要

以颗粒对为基础合成了三种液体选择性电极,用于选择氯化多巴胺。构建的电极由磷钼酸(多巴胺)、磷酸二正丁酯、邻苯二甲酸二正丁酯和膦酸二辛基苯酯作为增塑剂材料组成。研究发现,在 52.50 和 50.50 mV/decade 左右的成功 Nernstain 反应下,制备探针的构造是可行的。以 DBPH 和 DOPH 为增塑剂的电极的 Nernstain 反应分别为 52.50 和 50.50 mV/decade。发现药物形式的多巴胺最直接的浓度范围为:DBPH 约为 2.5×10-5-1.0×10-2 M,DOPH 约为 4.30×10-5 -1.0×10-1 M。DBPH 和 DOPH 的检出限分别为 2.31×10-6 和 5.63×10-6 M。63×10-6 M。第三种电极依靠磷酸二正丁酯(DPH),其非染色当量约为 19.10 mV/decade,浓度范围约为 2.2×10-5 -1.0×10-1 ,检测限相当于 6.35×10-6。实验应用中对 pH 值进行了评估,以获得 10-3M 的多巴胺浓度的最佳测定值。通过对 DBPH 和 DOPH 两种电极进行优化,在寿命、选择性、电位技术和测量精度方面都取得了良好的一致。同时,通过标准扩展、各种标准扩展和电位滴定,可以立即确定药物形式的多巴胺。
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Construction of Dopamine Hydrochloride Liquid Selective Electrodes
Three liquid selective electrodes were synthesized based on particle pair to selective dopamine chloride. The construction electrodes consist of phosphomolybdicacid (dopamine), di-n-butyl phosphate, Di-n-butyl phthalate, and di-octylphenyl phosphonate as plasticizers materials. The construction of preparing probes was examined potentially with successes Nernstain response around 52.50 and 50. 50 mV/decade for electrodes on both DBPH and DOPH were as plasticizers, respectively. The most direct ranges concentrations of dopamine in drug form were found to be around 2.5×10-5-1.0×10-2 for DBPH and 4.30×10-5 -1.0×10-1 M for DOPH. The detection limits were reached to 2.31×10-6 in DBPH and 5. 63×10-6 M in DOPH electrode type. While third electrode relied on di-n-butyl phosphate (DPH), a non-Nernstain equivalent of around 19.10 mV/decade with a range of concentration about 2.2×10-5 -1.0×10-1 with a detection limit equivalent to 6.35×10-6. The pH values in the experimental application were asses to obtain the best determination of dopamine concentration at 10-3M. The optimisation of both electrodes DBPH and DOPH achieved good agreements to lifetime, selectivity, potentiometric techniques and accuracy of measurements. At the same time the standard expansion, various standard expansions and potentiometric titration result in an immediate strategy for the assurance of dopamine in drug form.
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