心理疼痛治疗的积极影响:随机临床试验的补充分析。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-03-28 DOI:10.1037/rep0000557
Erica J Ho, Aaron P Turner, Mark P Jensen, Melissa A Day, Dawn M Ehde, Tracy M Anastas, Rhonda M Williams
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引用次数: 0

摘要

目的:临床试验通常将减轻症状作为主要结果,而忽视了具有潜在重要性的积极心理因素,尽管许多人可以而且确实在疼痛中生活得很好。患者报告结果测量信息系统(PROMIS)的社会心理疾病积极影响(PIIP)量表可评估患者在发病后对适应性社会心理功能(如应对和意义建构)的看法。本研究利用一项已完成的补充性和综合性慢性疼痛干预随机临床试验(RCT)的数据,评估了催眠(HYP)、正念冥想(MM)和疼痛心理教育(ED)对 PIIP 评分的影响。我们假设,对 PIIP 的治疗效果将反映 RCT 的主要疼痛强度结果,因此相对于 ED,HYP 和 MM 将在试验随访期间对 PIIP 带来更大的改善:我们的样本包括 262 名退伍军人,他们在治疗前和治疗后以及 3 个月和 6 个月的随访中填写了 PROMIS PIIP Short-Form 8a。在控制基线 PIIP、平均疼痛强度和基线疼痛前心理社会功能感知的情况下,我们使用线性回归法检验了各时间点 PIIP 的组间差异:结果:治疗后或 3 个月随访时,PIIP 没有明显的组间差异。然而,在6个月的随访中出现了组间差异:随机接受MM和HYP治疗的患者与随机接受ED治疗的患者相比,PIIP有所改善:结论:在疼痛干预的临床试验中,积极的心理社会结果是一个尚未开发的领域。本研究强调了在研究和临床环境中纳入积极心理学概念的潜在益处,并强调了理解人类在疾病和残疾面前蓬勃发展的重要性。(PsycInfo Database Record (c) 2024 APA,保留所有权利)。
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Positive impacts of psychological pain treatments: Supplementary analyses of a randomized clinical trial.

Objective: Clinical trials often focus on symptom reduction as a primary outcome, overlooking positive psychology factors of potential importance although many individuals can and do live well with pain. The Patient-Reported Outcomes Measurement Information System (PROMIS) Psychosocial Illness Impact-Positive (PIIP) scale assesses perceptions of adaptive psychosocial functioning (e.g., coping and meaning-making) after illness onset. This study evaluated the effects of hypnosis (HYP), mindfulness meditation (MM), and pain psychoeducation (ED) on PIIP scores, using data from a completed randomized clinical trial (RCT) of complementary and integrative chronic pain interventions. We hypothesized that treatment effects on PIIP would mirror the RCT's primary pain intensity outcome, such that HYP and MM, relative to ED, would lead to greater improvements in PIIP during trial follow-up.

Method: Our sample included 262 Veterans who completed the PROMIS PIIP Short-Form 8a at pre- and posttreatment and at 3- and 6-month follow-up. Linear regression was used to test between-group differences in PIIP at each time point, controlling for baseline PIIP, average pain intensity, and baseline perceptions of prepain psychosocial functioning.

Results: There were no significant between-group differences in PIIP at posttreatment or 3-month follow-up. However, group differences emerged at 6-month follow-up: individuals randomized to MM and HYP showed improved PIIP relative to those randomized to ED.

Conclusions: Positive psychosocial outcomes are a mostly untapped territory in clinical trials of pain interventions. The present work highlights the potential benefits of including positive psychology concepts in both research and clinical contexts, emphasizing the importance of understanding human flourishing in the presence of illness and disability. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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