磷脂酰乙醇(B-PEth)及其他直接和间接的酒精消费生物标志物。

International review of neurobiology Pub Date : 2024-01-01 Epub Date: 2024-03-19 DOI:10.1016/bs.irn.2024.03.004
Andrea de Bejczy
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引用次数: 0

摘要

在识别、预防和治疗酒精使用障碍时,正确估计酒精摄入量至关重要。由于自我报告的酒精摄入量存在偏差,因此客观标记物是首选。在酒精治疗策略和酒精研究中,易于使用的血液生物标志物是正确评估酒精消耗量的宝贵财富。特异性、累积性生物标志物磷脂酰乙醇反映了过去两周的饮酒量,与传统的生物标志物相比显示出其优越性,是一种有吸引力的酒精摄入量替代选择。
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Phosphatidylethanol (B-PEth) and other direct and indirect biomarkers of alcohol consumption.

When identifying, preventing and treating alcohol use disorder, a correct estimation of alcohol intake is essential. An objective marker is preferred as self-reported alcohol intake suffers from bias, and the use of alcohol biomarkers is increasing globally. An easy-to-use blood biomarker to correctly assess alcohol consumption is an invaluable asset in alcohol treatment strategies, as well as in alcohol research studies. The specific, cumulative, biomarker phosphatidylethanol, mirroring the past two weeks of consumption, has shown superiority over traditional biomarkers and is an attractive choice of proxy for alcohol intake.

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