霉菌毒素:综述动物和人类饲料和食品中霉菌毒素的类型、毒性、传统和最新的检测与应对技术

Eman M. El, El-Sherbeny
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引用次数: 0

摘要

霉菌毒素是一项全球性挑战,是影响食品和饲料的最严重危害之一。它是由各种致毒真菌自然产生的次级代谢物。由于其免疫抑制、致癌和致突变的特性,它可对动物和人类造成慢性或急性毒性。每年,霉菌毒素都会给动物饲料和畜牧业造成巨大的经济损失。人类受到霉菌毒素的影响,要么是间接食用了受霉菌毒素残留物污染的动物产品(肉、蛋、奶),要么是直接食用了受污染的食品(坚果、咖啡、玉米、大麦、小麦、花生、豌豆)及其副产品。本综述概述了动物饲料中最重要和最常见的霉菌毒素,以及霉菌毒素对动物健康和经济的影响。此外,还介绍了霉菌毒素分析检测技术的主要传统方法和先进方法,以及减轻和抵御饲料霉菌毒素污染的净化策略。有不同的分析技术可精确测定霉菌毒素的质量和数量。除其他最新的先进技术外,这些技术还包括荧光计、色谱设备和免疫技术。目前已开发出多种霉菌毒素解毒策略,包括物理、化学和生物策略,以减少或消除饲料原料或全价配合饲料中的霉菌毒素,但这些策略无法完全消除霉菌毒素的污染。因此,它们在满足实际应用要求方面的局限性或能力各不相同,这取决于许多因素,包括它们的结合效率、环境保护、饲料和食品安全、适口性或成本效益。
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Mycotoxins: Review on types, toxicity, conventional and updating techniques of detection and counteraction in feeds and foods of animals and human
M ycotoxins, a global challenge, represent one of the most significant hazards that affect foods and feeds. It produced naturally as secondary metabolites by various species of toxigenic fungi. It can cause chronic or acute toxicity due to their immunosuppressive, carcinogenic and mutagenic properties in animals and human. Every year, mycotoxins cause massive economic losses in the animal feed sector and animal hus-bandry. Human affected by mycotoxins either indirectly through consumption of contaminated animal products (meat, eggs and milk) by mycotoxins' residue or directly through consumption of contaminated foods (nuts, coffee, corn, barley, wheat, peanuts, peas) and their by-products. This review gives an overview of the most important and prevalent mycotoxins in animal feeds, health and economic mycotoxins impacts on animals. In addition, the main conventional and advanced approaches in mycotoxins analytical detection techniques and decontamination strategies to mitigate and counteract mycotoxin contamination of feedstuffs were also reported. There are different analytical techniques to precisely qualities and quantities mycotoxins. They included Fluorometer, chromatography-based devices and immunological based techniques besides other recent advanced techniques. Various my-cotoxins detoxification strategies have been developed included physical, chemical and biological strategies to reduce or eliminate mycotoxins in feed ingredients or complete compound feeds, however they cannot totally de-contaminate mycotoxins. Hence, they varied in their limitations or abilities to meet the requirements of practical application according to many factors including their binding efficiency, environmental protection, feeds and foods safety, palatability or cost-effectiveness.
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